Protein threading using parallel evolution strategy

被引:0
|
作者
Islam, Rafiqul [1 ]
Ngom, Alioune [1 ]
机构
[1] Univ Windsor, Sch Comp Sci, Windsor, ON N9C 1L2, Canada
基金
加拿大自然科学与工程研究理事会;
关键词
D O I
暂无
中图分类号
TP18 [人工智能理论];
学科分类号
081104 ; 0812 ; 0835 ; 1405 ;
摘要
The protein threading problem is the problem of determining the three-dimensional structure of a given but arbitrary protein sequence from a set of known structures of other proteins. This problem is known to be NP-hard and current computational approaches are time-consuming and data-intensive. In this paper, we propose an evolution strategy for protein threading. We also propose parallel methods for fast threading. We have obtained encouraging energy results as well as significant reduction in threading time.
引用
收藏
页码:2332 / 2339
页数:8
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