Recent developments and future directions in computational genomics

被引：45
|
作者：
Tsoka, S [1 ]
Ouzounis, CA [1 ]
机构：
[1] EMBL, European Bioinformat Inst, Computat Gen Grp, Res Programme,Cambridge Outstn, Cambridge CB10 1SD, England
来源：
FEBS LETTERS | 2000年 / 480卷 / 01期
基金：
英国医学研究理事会;
关键词：
genomics; bioinformatics; algorithm; molecular biology database; genomic context; systems modelling; knowledge representation;
D O I：
10.1016/S0014-5793(00)01776-2
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
Computational genomics is a subfield of computational biology that deals with the analysis of entire genome sequences. Transcending the boundaries of classical sequence analysis, computational genomics exploits the inherent properties of entire genomes by modelling them as systems. We review recent developments in the field, discuss in some detail a number of novel approaches that take into account the genomic context and argue that progress will be made by novel knowledge representation and simulation technologies. (C) 2000 Federation of European Biochemical Societies. Published by Elsevier Science B.V. All rights reserved.
引用
收藏
页码：42 / 48
页数：7
相关论文
共 50 条
  • [31] Genetic epidemiology of osteoarthritis: recent developments and future directions
    Hochberg, Marc C.
    Yerges-Armstrong, Laura
    Yau, Michelle
    Mitchell, Braxton D.
    CURRENT OPINION IN RHEUMATOLOGY, 2013, 25 (02) : 192 - 197
  • [32] In Vivo Osteocyte Mechanotransduction: Recent Developments and Future Directions
    Hinton, Paige V.
    Rackard, Susan M.
    Kennedy, Oran D.
    CURRENT OSTEOPOROSIS REPORTS, 2018, 16 (06) : 746 - 753
  • [33] Recent developments and the future of computational science on microstructure formation
    Miyazaki, T
    MATERIALS TRANSACTIONS, 2002, 43 (06) : 1266 - 1272
  • [34] Computational Photonics: Essentials, Recent Developments and Future Perspectives
    Obayya, Salah S. A.
    2018 35TH NATIONAL RADIO SCIENCE CONFERENCE (NRSC), 2018, : 3 - 3
  • [35] Advances in immunotherapy for cervical cancer: recent developments and future directions
    Sherer, Michael Vincent
    Kotha, Nikhil, V
    Williamson, Casey
    Mayadev, Jyoti
    INTERNATIONAL JOURNAL OF GYNECOLOGICAL CANCER, 2022, 32 (03) : 281 - 287
  • [36] Recent Developments and Future Directions of Wearable Skin Biosignal Sensors
    Kim, Dohyung
    Min, JinKi
    Ko, Seung Hwan
    ADVANCED SENSOR RESEARCH, 2024, 3 (02):
  • [37] Relevance Theory: Recent Developments, Current Challenges and Future Directions
    Scott, Kate
    JOURNAL OF PRAGMATICS, 2018, 123 : 113 - 115
  • [38] Raw-wool metrology: Recent developments and future directions
    Baxter, BP
    WOOL TECHNOLOGY AND SHEEP BREEDING, 2002, 50 (04): : 766 - 779
  • [39] Polymerization reactor modeling: A review of recent developments and future directions
    Kiparissides, C
    CHEMICAL ENGINEERING SCIENCE, 1996, 51 (10) : 1637 - 1659
  • [40] Using R in hydrology: a review of recent developments and future directions
    Slater, Louise J.
    Thirel, Guillaume
    Harrigan, Shaun
    Delaigue, Olivier
    Hurley, Alexander
    Khouakhi, Abdou
    Prosdocimi, Ilaria
    Vitolo, Claudia
    Smith, Katie
    HYDROLOGY AND EARTH SYSTEM SCIENCES, 2019, 23 (07) : 2939 - 2963
12345