Context: A classification system for lower urinary tract system (LUTS) dysfunction, based on urodynamics, could support the evaluation and management of this pathological condition. Objective: A new alphanumerical classification system is proposed for staging neurogenic and non-neurogenic LUTS dysfunction, according to the urodynamic evaluation. Evidence acquisition: This is a proposal based on experience from everyday clinical practice and represents an opinion open to discussion. Evidence synthesis: The purpose of this alphanumerical classification is the establishment of a simple, unified staging system describing all LUTS dysfunction situations, after a urodynamic evaluation, in a way that can help in diagnosis, treatment, health professionals' communication, education, and research. Conclusions: This alphanumerical classification for LUTS dysfunction could become a unified standard and a prerequisite for ensuring the quality of care in all resource settings. Moreover, it would be useful for the future to include a classification as part of LUTS dysfunction registration. Patient summary: A new alphanumerical classification system is presented. The purpose of this classification is the establishment of a simple, unified staging system describing entire lower urinary tract system dysfunction situations in a way that could help in diagnosis, treatment, health professionals' communication, education, and research. (c) 2017 European Association of Urology. Published by Elsevier B.V. All rights reserved.