Streptococcus pneumoniae serotype replacement in nasopharyngeal colonization in children vaccinated with PCV7, in Mexico

被引:5
|
作者
Elena Espinosa-de los Monteros, Luz [1 ]
Aguilar-Ituarte, Felipe [2 ]
Norberto Jimenez-Juarez, Rodolfo [3 ]
Rodriguez-Suarez, Romeo S. [4 ]
Gomez-Barreto, Demostenes [1 ]
机构
[1] Hosp Gen Manuel Gea Gonzalez, Mexico City 14080, DF, Mexico
[2] Hosp Infantil Mexico Fed Gomez, Mexico City, DF, Mexico
[3] Hosp Infectol, Cento Med Nacl La Raza, Inst Mexicano Seguro Social, Mexico City, DF, Mexico
[4] Secretaria Salud Mexico, Coordinac Asesores Secretaria Salud, Mexico City, DF, Mexico
来源
SALUD PUBLICA DE MEXICO | 2010年 / 52卷 / 01期
关键词
Streptococcus pneumoniae; nasopharinx; Mexico; PNEUMOCOCCAL CONJUGATE VACCINE; DAY-CARE-CENTERS; CARRIAGE; EMERGENCE; SERUM; IMMUNOGENICITY; ACQUISITION; ANTIBODIES; INFANTS; DISEASE;
D O I
10.1590/S0036-36342010000100003
中图分类号
R1 [预防医学、卫生学];
学科分类号
1004 ; 120402 ;
摘要
Objective.To assess the impact of pneumococcal conjugate vaccine (PCV7) immunization on pneumococcal nasopharyngeal colonization with S. pneumoniae (SPN). Material and Methods.We studied two groups with different vaccination schedules, group I (2-6 months of age) 3+1 and group II (7-11 months) 2+1, with a booster at 15 months. Nasopharyngeal cultures were obtained before administering each vaccination dose and after booster. Paired and global analyses were carried out of the proportions of children colonized by SPN, vaccine serotype, no vaccine serotype and resistance to penicillin. Results. A total of 183 children were enrolled; 93 in group I and 90 in group II. In group I, there was a decrease in vaccine serotypes in the third sample. In group II, there was an increase in non-vaccine serotypes and a decrease in vaccine serotypes before booster. Both groups showed a trend toward decreased resistance to penicillin. Conclusion. PCV7 caused serotype replacement in nasopharyngeal colonization before the booster.
引用
收藏
页码:4 / 13
页数:10
相关论文
共 50 条
  • [21] Nasopharyngeal colonization with Streptococcus pneumoniae in children receiving trimethoprim-sulfamethoxazole prophylaxis
    Abdel-Haq, N
    Abuhammour, W
    Asmar, B
    Thomas, R
    Dabbagh, S
    Gonzalez, R
    PEDIATRIC INFECTIOUS DISEASE JOURNAL, 1999, 18 (07) : 647 - 649
  • [22] Streptococcus pneumoniae Nasopharyngeal Carriage among PCV-10-Vaccinated HIV-1-Infected Children with Maintained Serological Memory in Ethiopia
    Lemma, Mahlet
    Bekele, Yonas
    Petkov, Stefan
    Hagglund, Moa
    Petros, Beyene
    Aseffa, Abraham
    Howe, Rawleigh
    Chiodi, Francesca
    PATHOGENS, 2020, 9 (03):
  • [23] Comparison of early effects of pneumococcal conjugate vaccines: PCV7, PCV10 and PCV13 on Streptococcus pneumoniae nasopharyngeal carriage in a population based study; The Palestinian-Israeli Collaborative Research (PICR)
    Abu Seir, Rania
    Azmi, Kifaya
    Hamdan, Ayob
    Namouz, Hanan
    Jaar, Fuad
    Jaber, Hanaa
    Rubin, Carmit
    Doron, Dafna
    Rahav, Galia
    Abdeen, Ziad
    Regev-Yochay, Gili
    PLOS ONE, 2018, 13 (11):
  • [24] Dynamic of pneumococcal nasopharyngeal carriage in children with acute otitis media following PCV7 introduction in France
    Cohen, R.
    Levy, C.
    Bonnet, E.
    Grondin, S.
    Desvignes, V.
    Lecuyer, A.
    Fritzell, B.
    Varon, E.
    VACCINE, 2010, 28 (37) : 6114 - 6121
  • [25] Nasopharyngeal colonization of infants in southern India with Streptococcus pneumoniae
    Jebaraj, R
    Cherian, T
    Raghupathy, P
    Brahmadathan, KN
    Lalitha, MK
    Thomas, K
    Steinhoff, MC
    EPIDEMIOLOGY AND INFECTION, 1999, 123 (03): : 383 - 388
  • [26] Pediatric complicated pneumonia and pneumococcal serotype replacement: trends in hospitalized children pre and post introduction of routine vaccination with Pneumococcal Conjugate Vaccine (PCV7)
    Thea K. Chibuk
    Joan L. Robinson
    Dawn S. Hartfield
    European Journal of Pediatrics, 2010, 169 : 1123 - 1128
  • [27] Early Streptococcus pneumoniae serotype changes in Utah adults after the introduction of PCV13 in children
    Kendall, Brian A.
    Dascomb, Kristin K.
    Mehta, Rajesh R.
    Stockmann, Chris
    Mason, Edward O.
    Ampofo, Krow
    Pavia, Andrew T.
    Byington, Carrie L.
    VACCINE, 2016, 34 (04) : 474 - 478
  • [28] Nasopharyngeal Carriage, Antimicrobial Resistance, and Serotype Distribution of Streptococcus pneumoniae in Children Under Five in Lebanon: Baseline Data Prior to PCV13 Introduction
    Rafei, Rayane
    Zaylaa, Mazen
    Diab, Mohamad
    Kassem, Issmat I.
    El Omari, Khaled
    Halimeh, Fatima B.
    El Moujaber, Grace
    Achour, Afaf
    Ismail, Bassel
    Mallat, Hassan
    Hamze, Monzer
    Dabboussi, Fouad
    Osman, Marwan
    ANTIBIOTICS-BASEL, 2025, 14 (02):
  • [29] Pediatric complicated pneumonia and pneumococcal serotype replacement: trends in hospitalized children pre and post introduction of routine vaccination with Pneumococcal Conjugate Vaccine (PCV7)
    Chibuk, Thea K.
    Robinson, Joan L.
    Hartfield, Dawn S.
    EUROPEAN JOURNAL OF PEDIATRICS, 2010, 169 (09) : 1123 - 1128
  • [30] Prevalence of Streptococcus pneumoniae and Staphylococcus aureus nasopharyngeal colonization in healthy children in the United States
    Immergluck, LC
    Kanungo, S
    Schwartz, A
    McIntyre, A
    Schreckenberger, PC
    Diaz, PS
    EPIDEMIOLOGY AND INFECTION, 2004, 132 (02): : 159 - 166