Element transfer from extract of greater celandine (Chelidonium majus L.)

Greater celandine (Chelidonium majus L.) is used internally as a herbal remedy besides external applications. It was supposed that the elements besides organic compounds in greater celandine also have favourable effect as adjuvants, therefore, the aim of the study was to evaluate the bioavailability of the elements. The element transfer through the gastrointestinal system was measured by in vitro model from the pressed extract into buffer solutions with different pH (stomach pH= 1. 1, intestine pH=2.8, plasma pH=7.5). It was stated that the elements (Al, B, Ba, Ca, Cu, Fe, Mg, Mn, S, Zn) were able to be absorbed through the stomach-bowel system, since they passed through the membrane. The transfer of the elements from the latex into the different buffer solutions greatly depends on the element and the pH of applied buffer Solution. The transfer of the elements from the latex ranged between 0.9% (Ca into buffer solution pH=7.5) and 59.3% (B into buffer solution pH=2.8). The transfer of the highest amount of elements was observed in the case of buffer solution pH=2.8, and less transferable elements were Ca with 33.64% and Mg with 33.89% of the initial value. On the basis of results, it can be stated that the elements are able to transfer through the gastrointestinal system and may have adjuvant effects.