CONTRAST AGENT MICROBUBBLE JETTING DURING INITIAL INTERACTION WITH 200-KHZ FOCUSED ULTRASOUND

被引:18
|
作者
Cleve, Sarah [1 ]
Inserra, Claude [2 ]
Prentice, Paul [3 ]
机构
[1] Univ Lyon, Ecole Cent Lyon, INSA Lyon, CNRS,LMFA,UMR 5509, Ecully, France
[2] Univ Lyon 1, Ctr Leon Berard, INSERM, LabTAU, Lyon, France
[3] Univ Glasgow, Ctr Med & Ind Ultrason, CavLab, Glasgow, Lanark, Scotland
来源
ULTRASOUND IN MEDICINE AND BIOLOGY | 2019年 / 45卷 / 11期
基金
英国工程与自然科学研究理事会; 欧洲研究理事会;
关键词
Microbubble; Jetting; Focused ultrasound; Cavitation;
D O I
10.1016/j.ultrasmedbio.2019.08.005
中图分类号
O42 [声学];
学科分类号
070206 ; 082403 ;
摘要
The initial response of microbubbles flowing through a 500-mu m polycarbonate capillary to a burst of 200-kHz focused ultrasound, at peak-negative pressure amplitudes from 0.7-1.5 MPa, was investigated with dual-perspective high-speed imaging. Directed jetting through the acoustic focus is demonstrated according to the pressure gradients acting across the cavitating microbubbles. At lower amplitudes, repeated microbubble-jetting is accompanied by sudden, intermittent translation. At higher amplitudes a rebound jet also forms, before disintegration into a cavitation cloud. (C) 2019 The Author(s). Published by Elsevier Inc. on behalf of World Federation for Ultrasound in Medicine & Biology.
引用
收藏
页码:3075 / 3080
页数:6
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