Synthesis and biological activity of cyanopyridine, isoxazole and pyrazoline derivatives having thymol moiety

被引：0
|
作者：
Desai, JM [1 ]
Shah, VH [1 ]
机构：
[1] Saurashtra Univ, Dept Chem, Rajkot 360005, Gujarat, India
来源：
INDIAN JOURNAL OF CHEMISTRY SECTION B-ORGANIC CHEMISTRY INCLUDING MEDICINAL CHEMISTRY | 2003年 / 42卷 / 02期
关键词：
D O I：
暂无
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
New 4-acetoacetamido thymol 1, 4-(substituted benzalacetoacetamido)-thymols 2a-j, 4-(2'-amino-3'-cyano-4'-arylpyridin-6'-yl-acetamido) thymols 3a-j, 4-(5'-arylisoxazol-3'-yl-acetamido) thymols 4a-j and 4-(1'-N(H)/acetyl-5'-arylpyrazolin-3'-yl-acetamido) thymols 5a-t have been synthesised and screened for their antimicrobial activity. The products display moderate to good activities. The structures of the products 1, 2a-j, 3a-j, 4a-j and 5a-t have been elucidated by elemental analyses and spectral data.
引用
收藏
页码：382 / 385
页数：4
相关论文
共 50 条
  • [21] SYNTHESIS AND BIOLOGICAL-ACTIVITY OF SOME HALOANILIDO PYRAZOLINE AND ISOXAZOLINE DERIVATIVES
    MANDAL, NK
    SINHA, R
    BANERJEE, KP
    JOURNAL OF THE INDIAN CHEMICAL SOCIETY, 1984, 61 (11-1) : 979 - 981
  • [22] Synthesis, antitubercular and antimicrobial activities of some new pyrazoline and isoxazole derivatives
    Vyas, D. H.
    Tala, S. D.
    Dhaduk, M. F.
    Akbari, J. D.
    Joshi, H. S.
    JOURNAL OF THE INDIAN CHEMICAL SOCIETY, 2007, 84 (11) : 1140 - 1144
  • [23] Synthesis and cytotoxic activity of tanshinone I derivatives having azacyclo moiety
    Wu, Liqiang
    Yang, Xiaojuan
    Journal of Chemical and Pharmaceutical Research, 2014, 6 (02) : 442 - 445
  • [24] Synthesis and Configuration of Novel Isoxazole Derivatives Containing Pyrazole Moiety
    Zhou, Yinglei
    Shen, Songwei
    Liu, Fangming
    CHINESE JOURNAL OF ORGANIC CHEMISTRY, 2010, 30 (09) : 1342 - 1346
  • [25] Synthesis, Molecular Docking and Antimicrobial Activity of α, β-Unsaturated Ketone Exchange Moiety for Chalcone and Pyrazoline Derivatives
    Farooq, Saba
    Ngaini, Zainab
    CHEMISTRYSELECT, 2020, 5 (32): : 9974 - 9979
  • [26] Novel Pyrazole-Hydrazone Derivatives Containing an Isoxazole Moiety: Design, Synthesis, and Antiviral Activity
    Yang, Zaibo
    Li, Pei
    Gan, Xiuhai
    MOLECULES, 2018, 23 (07):
  • [27] Assessment of Antimicrobial Activity, Reactivity and Non-Linear Optical Properties of New Pyrazoline Derivatives having Pyrrole moiety
    Rawat, Poonam
    Singh, R. N.
    Sahu, Sangeeta
    Niranjan, Priydarshni
    Rani, Himanshu
    Saxena, Rajat
    Ahmad, Sartaj
    CHEMISTRYSELECT, 2016, 1 (13): : 4008 - 4015
  • [28] Synthesis of pyrazoline and isoxazole derivatives bearing chloroquinoline nucleus as potential antimicrobial agents
    Dobaria, AV
    Patel, JR
    Parekh, HH
    INDIAN JOURNAL OF CHEMISTRY SECTION B-ORGANIC CHEMISTRY INCLUDING MEDICINAL CHEMISTRY, 2003, 42 (08): : 2019 - 2022
  • [29] Synthesis, crystal structure, biological activity and theoretical calculations of novel isoxazole derivatives
    Jin, R. Y.
    Sun, X. H.
    Liu, Y. F.
    Long, W.
    Chen, B.
    Shen, S. Q.
    Ma, H. X.
    SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY, 2016, 152 : 226 - 232
  • [30] Synthesis and antibacterial activity of new carbapenems containing isoxazole moiety
    Kang, YK
    Shin, KJ
    Yoo, KH
    Seo, KJ
    Hong, CY
    Lee, CS
    Park, SY
    Kim, DJ
    Park, SW
    BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2000, 10 (02) : 95 - 99
12345