Hydrodynamics of triple emulsion droplet generation in a flow-focusing microfluidic device
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作者:
Yu, Wei
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机构:
Yangzhou Univ, Coll Elect Energy & Power Engn, Yangzhou 225009, Jiangsu, Peoples R ChinaYangzhou Univ, Coll Elect Energy & Power Engn, Yangzhou 225009, Jiangsu, Peoples R China
Yu, Wei
[1
]
Li, Bo
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机构:
China Acad Engn Phys, Laser Fus Res Ctr, Mianyang 621900, Sichuan, Peoples R ChinaYangzhou Univ, Coll Elect Energy & Power Engn, Yangzhou 225009, Jiangsu, Peoples R China
Li, Bo
[2
]
Liu, Xiangdong
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Yangzhou Univ, Coll Elect Energy & Power Engn, Yangzhou 225009, Jiangsu, Peoples R ChinaYangzhou Univ, Coll Elect Energy & Power Engn, Yangzhou 225009, Jiangsu, Peoples R China
Liu, Xiangdong
[1
]
Chen, Yongping
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机构:
Yangzhou Univ, Coll Elect Energy & Power Engn, Yangzhou 225009, Jiangsu, Peoples R China
Suzhou Univ Sci & Technol, Sch Environm Sci & Engn, Jiangsu Key Lab Micro & Nano Heat Fluid Flow Tech, Suzhou 215009, Jiangsu, Peoples R ChinaYangzhou Univ, Coll Elect Energy & Power Engn, Yangzhou 225009, Jiangsu, Peoples R China
Chen, Yongping
[1
,3
]
机构:
[1] Yangzhou Univ, Coll Elect Energy & Power Engn, Yangzhou 225009, Jiangsu, Peoples R China
[2] China Acad Engn Phys, Laser Fus Res Ctr, Mianyang 621900, Sichuan, Peoples R China
A numerical research is conducted to investigate the triple emulsion droplet generation in a threedimensional axisymmetric flow-focusing device. The simulation predicts three flow regimes: dripping, jetting, and threading. The hydrodynamics underlying the droplet generation and effects of operation conditions on the droplet generation are clarified. An increase in flow rate of one dispersed phase results in the larger droplet enclosing this phase and smaller droplet enclosed by this phase. As the interfacial tension between any two phases increases or viscosity of any phases decrease, the flow regime transits from jetting to dripping, accompanied by a decrease in the droplet size. Increasing the interfacial tension coefficient or decreasing the viscosity under both two regimes can increase the droplet size. Additionally, regime diagrams for single, middle, and triple emulsion droplet generation are compared, and an empirical equation is proposed to predict the flow regime transition. (c) 2021 Elsevier Ltd. All rights reserved.
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Boston Univ, Dept Biomed Engn, Boston, MA 02215 USA
Biol Design Ctr, 610 Commonwealth Ave, Boston, MA 02215 USABoston Univ, Dept Biomed Engn, Boston, MA 02215 USA
Lashkaripour, Ali
Rodriguez, Christopher
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MIT, Computat & Syst Biol, 77 Massachusetts Ave, Cambridge, MA 02139 USABoston Univ, Dept Biomed Engn, Boston, MA 02215 USA
Rodriguez, Christopher
Mehdipour, Noushin
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Biol Design Ctr, 610 Commonwealth Ave, Boston, MA 02215 USA
Boston Univ, Div Syst Engn, Boston, MA 02215 USABoston Univ, Dept Biomed Engn, Boston, MA 02215 USA
Mehdipour, Noushin
Mardian, Rizki
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Biol Design Ctr, 610 Commonwealth Ave, Boston, MA 02215 USA
Boston Univ, Dept Elect & Comp Engn, Boston, MA 02215 USABoston Univ, Dept Biomed Engn, Boston, MA 02215 USA
Mardian, Rizki
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McIntyre, David
Ortiz, Luis
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Biol Design Ctr, 610 Commonwealth Ave, Boston, MA 02215 USA
Boston Univ, Dept Mol Biol Cell Biol & Biochem, Boston, MA 02215 USABoston Univ, Dept Biomed Engn, Boston, MA 02215 USA
Ortiz, Luis
Campbell, Joshua
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Boston Univ, Dept Med, Boston, MA 02215 USABoston Univ, Dept Biomed Engn, Boston, MA 02215 USA
Campbell, Joshua
Densmore, Douglas
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Biol Design Ctr, 610 Commonwealth Ave, Boston, MA 02215 USA
Boston Univ, Dept Elect & Comp Engn, Boston, MA 02215 USABoston Univ, Dept Biomed Engn, Boston, MA 02215 USA
机构:
Harbin Inst Technol, Sch Mechatron Engn, West Da Zhi St 92, Harbin 150001, Heilongjiang, Peoples R ChinaHarbin Inst Technol, Sch Mechatron Engn, West Da Zhi St 92, Harbin 150001, Heilongjiang, Peoples R China
Jiang, Tianyi
Wu, Hao
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Harbin Inst Technol, Sch Mechatron Engn, West Da Zhi St 92, Harbin 150001, Heilongjiang, Peoples R China
City Univ Hong Kong, Dept Mech Engn, Kowloon, Hong Kong 999077, Peoples R ChinaHarbin Inst Technol, Sch Mechatron Engn, West Da Zhi St 92, Harbin 150001, Heilongjiang, Peoples R China
Wu, Hao
Liu, Shuofu
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Harbin Inst Technol, Sch Mechatron Engn, West Da Zhi St 92, Harbin 150001, Heilongjiang, Peoples R ChinaHarbin Inst Technol, Sch Mechatron Engn, West Da Zhi St 92, Harbin 150001, Heilongjiang, Peoples R China
Liu, Shuofu
Yan, Hui
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Harbin Inst Technol, Sch Mechatron Engn, West Da Zhi St 92, Harbin 150001, Heilongjiang, Peoples R ChinaHarbin Inst Technol, Sch Mechatron Engn, West Da Zhi St 92, Harbin 150001, Heilongjiang, Peoples R China
Yan, Hui
Jiang, Hongyuan
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Harbin Inst Technol, Sch Mechatron Engn, West Da Zhi St 92, Harbin 150001, Heilongjiang, Peoples R ChinaHarbin Inst Technol, Sch Mechatron Engn, West Da Zhi St 92, Harbin 150001, Heilongjiang, Peoples R China
机构:
Biol Design Ctr, 610 Commonwealth Ave, Boston, MA 02215 USA
Boston Univ, Biomed Engn Dept, Boston, MA USABiol Design Ctr, 610 Commonwealth Ave, Boston, MA 02215 USA
Lashkaripour, Ali
Rodriguez, Christopher
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Louisiana Tech Univ, Dept Cyber Engn, Ruston, LA 71270 USABiol Design Ctr, 610 Commonwealth Ave, Boston, MA 02215 USA
Rodriguez, Christopher
Ortiz, Luis
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机构:
Biol Design Ctr, 610 Commonwealth Ave, Boston, MA 02215 USA
Boston Univ, Dept Mol Biol Cell Biol & Biochem, Boston, MA 02215 USABiol Design Ctr, 610 Commonwealth Ave, Boston, MA 02215 USA
Ortiz, Luis
Densmore, Douglas
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机构:
Biol Design Ctr, 610 Commonwealth Ave, Boston, MA 02215 USA
Boston Univ, Dept Elect & Comp Engn, Boston, MA 02215 USABiol Design Ctr, 610 Commonwealth Ave, Boston, MA 02215 USA