Enantioselective benzoin condensation catalyzed by spirocyclic terpene-based N-heterocyclic carbenes

被引：12
|
作者：
Rafinski, Zbigniew [1 ]
机构：
[1] Nicolaus Copernicus Univ Torun, Fac Chem, 7 Gagarin St, PL-87100 Torun, Poland
来源：
TETRAHEDRON | 2016年 / 72卷 / 15期
关键词：
N-Heterocyclic carbenes; Benzoin condensation; Asymmetric synthesis; Acyloins; Terpenoids; TRIAZOLIUM SALTS; THIAZOLIUM;
D O I：
10.1016/j.tet.2016.02.049
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
The synthesis of new chiral spirocyclic triazolium salts, derived from (1S)-fenchone and (1R)-camphorquinone, are described. These salts, which are N-heterocyclic carbene precatalysts, were successfully employed in the catalytic asymmetric benzoin condensation affording acyloins with good yields and moderate enantioselectivities. (C) 2016 Elsevier Ltd. All rights reserved.
引用
收藏
页码：1860 / 1867
页数：8
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