The role of heat shock proteins in metastatic colorectal cancer: A review

被引：19

作者：

Javid, Hossein ^{[1
,2
]}

Hashemian, Pedram ^{[3
]}

Yazdani, Shaghayegh ^{[4
,5
]}

Mashhad, Alireza Sharbaf ^{[4
]}

Karimi-Shahri, Mehdi ^{[6
,7
]}

机构：

[1] Mashhad Univ Med Sci, Fac Med, Dept Clin Biochem, Mashhad, Razavi Khorasan, Iran

[2] Varastegan Inst Med Sci, Dept Med Lab Sci, Mashhad, Razavi Khorasan, Iran

[3] Jahad Daneshgahi Inst, Jahad Daneshgahi Res Comm, Mashhad, Razavi Khorasan, Iran

[4] Mashhad Univ Med Sci, Dept Med Lab Sci, Mashhad, Razavi Khorasan, Iran

[5] Ilam Univ Med Sci, Dept Med Lab Sci, Ilam, Iran

[6] Mashhad Univ Med Sci, Sch Med, Dept Pathol, Mashhad, Razavi Khorasan, Iran

[7] Gonabad Univ Med Sci, Sch Med, Dept Pathol, Gonabad, Iran

来源：

JOURNAL OF CELLULAR BIOCHEMISTRY | 2022年 / 123卷 / 11期

关键词：

colorectal cancer (CRC); heat shock proteins (HSPs); metastatic colorectal cancer; ALPHA-B-CRYSTALLIN; EPITHELIAL-MESENCHYMAL TRANSITION; ENDOTHELIAL GROWTH-FACTOR; COLON-CANCER; BETA-CATENIN; TUMOR-SUPPRESSOR; THERAPEUTIC TARGET; BREAST-CANCER; CELL-CYCLE; HEAT-SHOCK-PROTEIN-60; HSP60;

D O I：

10.1002/jcb.30326

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Heat shock proteins (HSPs) are a large molecular chaperone family classified by their molecular weights, including HSP27, HSP40, HSP60, HSP70, HSP90, and HSP110. HSPs are likely to have antiapoptotic properties and participate actively in various processes such as tumor cell proliferation, invasion, metastases, and death. In this review, we discuss comprehensively the functions of HSPs associated with the progression of colorectal cancer (CRC) and metastasis and resistance to cancer therapy. Taken together, HSPs have numerous clinical applications as biomarkers for cancer diagnosis and prognosis and potential therapeutic targets for CRC and its related metastases.

引用

页码：1704 / 1735

页数：32

共 50 条

[21] The role of heat shock proteins in atherosclerosis
Wick, Georg
Jakic, Bojana
Buszko, Maja
Wick, Marius C.
Grundtman, Cecilia
NATURE REVIEWS CARDIOLOGY, 2014, 11 (09) : 516 - 529
[22] Role of heat shock proteins in atherosclerosis
Xu, QB
ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY, 2002, 22 (10) : 1547 - 1559
[23] Heat shock proteins in human cancer
Sarto, C
Binz, PA
Mocarelli, P
ELECTROPHORESIS, 2000, 21 (06) : 1218 - 1226
[24] HEAT-SHOCK PROTEINS AND CANCER
SWARTZBERG, D
JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION, 1995, 274 (04): : 291 - 291
[25] Targeting heat shock proteins in cancer
Jego, Gaetan
Hazoume, Adonis
Seigneuric, Renaud
Garrido, Carmen
CANCER LETTERS, 2013, 332 (02) : 275 - 285
[26] Heat Shock Proteins and Breast Cancer
Zhang, Miao
Bi, Xiaowen
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2024, 25 (02)
[27] Heat Shock Proteins in Cancer Diagnostics
Guliy, O. I.
Staroverov, S. A.
Dykman, L. A.
APPLIED BIOCHEMISTRY AND MICROBIOLOGY, 2023, 59 (04) : 395 - 407
[28] Heat Shock Proteins in Cancer Immunotherapy
Das, Jugal Kishore
Xiong, Xiaofang
Ren, Xingcong
Yang, Jin-Ming
Song, Jianxun
JOURNAL OF ONCOLOGY, 2019, 2019
[29] Heat shock proteins in cancer therapy
Lukacs, KV
Pardo, OE
Colston, MJ
Geddes, DM
Alton, EWFW
CANCER GENE THERAPY: PAST ACHIEVEMENTS AND FUTURE CHALLENGES, 2000, 465 : 363 - 368
[30] Heat Shock Proteins in Cancer Diagnostics
O. I. Guliy
S. A. Staroverov
L. A. Dykman
Applied Biochemistry and Microbiology, 2023, 59 : 395 - 407

← 1 2 3 4 5 →