Determination of Ursolic and Oleanolic Acid in Sambuci Fructus

被引：12

作者：

Glensk, Michal ^{[1
]}

Glinski, Jan A. ^{[2
]}

Wlodarczyk, Maciej ^{[1
]}

Stefanowicz, Piotr ^{[3
]}

机构：

[1] Wroclaw Med Univ, Dept Pharmacognosy, PL-50556 Wroclaw, Poland

[2] Planta Analyt LLC, Danbury, CT 06810 USA

[3] Univ Wroclaw, Fac Chem, PL-50383 Wroclaw, Poland

来源：

CHEMISTRY & BIODIVERSITY | 2014年 / 11卷 / 12期

关键词：

LEAVES; HPLC;

D O I：

10.1002/cbdv.201400118

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Elderberries are used in the preparation of pie, jelly, punch, wine, or liqueur, as well as in many herbal remedies and food supplements. Elderberry products may provide diaphoretic, diuretic, antioxidant, and immunostimulant activities that offer protection against cold and flu. Herein, we report for the first time the qualitative and quantitative evaluation of two isomeric triterpenoids isolated from Sambuci fructus. The analysis revealed that ursolic acid and oleanolic acid are present in Sambuci fructus. The average concentration of ursolic acid was ca. three times higher than the concentration of oleanolic acid. The triterpenoids were detected and quantified using chromatographic methods such as TLC and HPLC. Spectroscopic techniques, including HR-MS and 2D-NMR, allowed unequivocal structure determination.

引用

页码：1939 / 1944

页数：6

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