Isolation of genomic fragments from polymorphic regions by representational difference analysis

被引：4
|
作者：
Baldocchi, RA [1 ]
Flaherty, L [1 ]
机构：
[1] David Axelrod Inst Publ Hlth, Wadsworth Ctr, Lab Dev Genet, Mol Genet Program, Albany, NY 12201 USA
来源：
METHODS-A COMPANION TO METHODS IN ENZYMOLOGY | 1997年 / 13卷 / 04期
关键词：
D O I：
10.1006/meth.1997.0542
中图分类号：
Q5 [生物化学];
学科分类号：
071010 ; 081704 ;
摘要：
Representational difference analysis is an effective technique for isolating the differences between two nearly identical genomes. We have found the technique to be extremely valuable in our analyses of mouse germline mutations. We also present several technical improvements in the procedure that make it more efficient and reliable. (C) 1997 Academic Press.
引用
收藏
页码：337 / 346
页数：10
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