Electrochemical Determination of Amoxicillin on a Poly(Acridine Orange) Modified Glassy Carbon Electrode

被引：19

作者：

Agin, Fatma ^{[1
]}

机构：

[1] Karadeniz Tech Univ, Fac Pharm, Dept Analyt Chem, TR-61080 Trabzon, Turkey

来源：

ANALYTICAL LETTERS | 2016年 / 49卷 / 09期

关键词：

Acridine orange; amoxicillin; modified glassy carbon electrode; poly(acridine orange); FILM-MODIFIED ELECTRODE; PASTE ELECTRODE; URIC-ACID; VOLTAMMETRIC DETERMINATION; BIOSENSOR; SENSOR; BLUE); OXIDATION; DOPAMINE; BEHAVIOR;

D O I：

10.1080/00032719.2015.1101602

中图分类号：

O65 [分析化学];

学科分类号：

070302 ; 081704 ;

摘要：

The electrooxidative behavior of amoxicillin was investigated on a poly(acridine orange) modified glassy carbon electrode from pH 5.0 to 8.0 by cyclic, differential pulse, and square wave voltammetry. The electrochemistry of amoxicillin was shown to be irreversible and diffusion controlled using the poly(acridine orange) modified electrode. Amoxicillin was determined by differential pulse and square wave voltammetry in 0.04M Britton-Robinson buffer at pH 5.0. Calibration curves were linear between 0.4 and 20 mu M with detection limits of 1.87x10(-3)mu M and 1.55x10(-2)mu M for differential pulse voltammetry and square wave voltammetry, respectively. The developed methods provided high selectivity, precision, and accuracy and were employed for the determination of amoxicillin in pharmaceuticals and human serum.

引用

页码：1366 / 1378

页数：13

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