Synthesis and immobilization of ceramide analogs on silica particles

被引：18
|
作者：
Yin, JM [1 ]
Liu, HL [1 ]
Pidgeon, C [1 ]
机构：
[1] Purdue Univ, Sch Pharm, Dept Med Chem & Mol Pharmacol, W Lafayette, IN 47907 USA
来源：
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS | 1998年 / 8卷 / 02期
基金：
美国国家科学基金会;
关键词：
D O I：
10.1016/S0960-894X(97)10217-7
中图分类号：
R914 [药物化学];
学科分类号：
100701 ;
摘要：
Ceramides are the major lipid components of the stratum corneum, the major permeability barrier of the skin. Here we report a chemical synthesis of ceramide analogs covalently bonded on the silica particles, that can be used to predict the skin permeability of chemicals via HPLC methods. (C) 1998 Elsevier Science Ltd. All rights reserved.
引用
收藏
页码：179 / 182
页数：4
相关论文
共 50 条
  • [31] Antibacterial activity of ceramide and ceramide analogs against pathogenic Neisseria
    Jérôme Becam
    Tim Walter
    Anne Burgert
    Jan Schlegel
    Markus Sauer
    Jürgen Seibel
    Alexandra Schubert-Unkmeir
    Scientific Reports, 7
  • [32] Synthesis of Mesoporous Silica Nanowires and Their Application in Enzyme Immobilization
    Liu, Peng
    Liu, Xinlong
    An, Na
    Wang, Peng
    2021 5TH INTERNATIONAL CONFERENCE ON ADVANCES IN ENERGY, ENVIRONMENT AND CHEMICAL SCIENCE (AEECS 2021), 2021, 245
  • [33] Synthesis and characterization of nanoporous silica support for enzyme immobilization
    Kim, JK
    Park, JK
    Kim, HK
    COLLOIDS AND SURFACES A-PHYSICOCHEMICAL AND ENGINEERING ASPECTS, 2004, 241 (1-3) : 113 - 117
  • [34] SYNTHESIS AND GROWTH OF COLLOIDAL SILICA PARTICLES
    COENEN, S
    DEKRUIF, CG
    JOURNAL OF COLLOID AND INTERFACE SCIENCE, 1988, 124 (01) : 104 - 110
  • [35] Synthesis of spherical porous silica particles
    Mori, Hideo
    Yamashita, Hiroshi
    Nakamura, Kunihiko
    Maekawa, Takashi
    Journal of the Ceramic Society of Japan. International ed., 1993, 101 (10): : 1149 - 1151
  • [36] SYNTHESIS OF SPHERICAL POROUS SILICA PARTICLES
    MORI, H
    YAMASHITA, H
    NAKAMURA, K
    MAEKAWA, T
    NIPPON SERAMIKKUSU KYOKAI GAKUJUTSU RONBUNSHI-JOURNAL OF THE CERAMIC SOCIETY OF JAPAN, 1993, 101 (10): : 1180 - 1183
  • [37] Controlled synthesis of monodisperse silica particles
    Liang, Xiao
    Lian, Lixian
    Liu, Ying
    Kong, Qingquan
    Wang, Li
    MICRO & NANO LETTERS, 2016, 11 (09): : 532 - 534
  • [38] PHOTOAFFINITY-LABELING OF SIALYTRANSFERASE - SYNTHESIS AND PROPERTIES OF PHOTOREACTIVE LACTOSYL CERAMIDE ANALOGS
    HASHIMOTO, M
    KURIHARA, H
    SANAI, Y
    HIDARI, K
    NAGAI, Y
    KANAOKA, Y
    HATANAKA, Y
    JOURNAL OF PHARMACOBIO-DYNAMICS, 1992, 15 (07): : S94 - S94
  • [39] Synthesis and characterization of novel ceramide analogs for induction of apoptosis in human cancer cells
    Bieberich, E
    Hu, B
    Silva, J
    MacKinnon, S
    Yu, RK
    Fillmore, H
    Broaddus, WC
    Ottenbrite, RM
    CANCER LETTERS, 2002, 181 (01) : 55 - 64
  • [40] Synthesis and biological evaluation of a new series of sulphonamide-containing ceramide analogs
    Booker, Sydney
    Goyal, Navneet
    Foroozesh, Maryam
    ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 2018, 255
12345