Prompt and Successful Toxin-Targeting Treatment of Three Patients with Necrotizing Pneumonia Due to Staphylococcus aureus Strains Carrying the Panton-Valentine Leukocidin Genes

被引：50
|
作者：
Rouzic, Nicolas [1 ,2 ,3 ,4 ]
Janvier, Frederic [5 ,6 ]
Libert, Nicolas [6 ,7 ]
Javouhey, Etienne [8 ]
Lina, Gerard [1 ,2 ,3 ,4 ]
Nizou, Jacques-Yves [5 ,6 ]
Pasquier, Pierre [9 ]
Stamm, Didier [8 ]
Brinquin, Louis [6 ,7 ]
Pelletier, Christophe [9 ]
Vandenesch, Francois [1 ,2 ,3 ,4 ]
Floret, Daniel [8 ]
Etienne, Jerome [1 ,2 ,3 ,4 ]
Gillet, Yves [1 ,2 ,3 ,4 ,8 ]
机构：
[1] Univ Lyon, F-69008 Lyon, France
[2] Univ Lyon 1, Fac Lyon Est, F-69008 Lyon, France
[3] Ctr Natl Reference Staphylocoques, Inserm EU851, F-69008 Lyon, France
[4] Hosp Civils Lyon, Ctr Biol Est, F-69500 Bron, France
[5] Hop Instruct Armees Val Grace, Serv Biol Med, Paris, France
[6] Ecole Val Grace, Paris, France
[7] Hop Instruct Armees Val Grace, Serv Reanimat, Paris, France
[8] Hop Femme Mere Enfant, Serv Urgences & Reanimat Pediat, Bron, France
[9] Hop Instruct Armees Begin, Serv Reanimat, St Mande, France
来源：
JOURNAL OF CLINICAL MICROBIOLOGY | 2010年 / 48卷 / 05期
关键词：
COMMUNITY-ACQUIRED PNEUMONIA; INFLUENZA SEASON; ANTIBIOTICS; MORTALITY;
D O I：
10.1128/JCM.01892-09
中图分类号：
Q93 [微生物学];
学科分类号：
071005 ; 100705 ;
摘要：
Three patients with extensive necrotizing pneumonia due to Panton-Valentine leukocidin-positive Staphylococcus aureus strains and with aggravating factors (leukopenia count of less than 3 x 10(9)/liter in all three cases and hemoptysis in two cases) were successfully treated with toxin-suppressing agents introduced rapidly after hospital admission.
引用
收藏
页码：1952 / 1955
页数：4
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