Synthesis of pentaarabinofuranosyl structure motif a of Mycobacterium tuberculosis

被引:73
|
作者
Mereyala, HB [1 ]
Hotha, S [1 ]
Gurjar, MK [1 ]
机构
[1] Indian Inst Chem Technol, Hyderabad 500007, Andhra Pradesh, India
关键词
D O I
10.1039/a707796c
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
The first synthesis of motif A, the branched chain arabino-furanosyl pentasaccharide [t-beta-Araf-(1 --> 2)-alpha-D-Araf](2)- 3,5-alpha-D-Araf-(1 --> 5) which constitutes the major humoral immunological epitope in the arabinogalactan cell wall of Mycobacterium tuberculosis is described.
引用
收藏
页码:685 / 686
页数:2
相关论文
共 50 条
  • [1] Synthesis of a tetrasaccharide present in motif B of the Mycobacterium tuberculosis cell wall
    Heng, LS
    Mei, XD
    Yao, Z
    Ning, J
    LETTERS IN ORGANIC CHEMISTRY, 2005, 2 (08) : 749 - 751
  • [2] An efficient synthesis of a dimer of the tetrasaccharide present in motif B of the Mycobacterium tuberculosis cell wall
    Mei, XD
    Ning, J
    SYNLETT, 2005, (15) : 2267 - 2272
  • [3] Biosynthesis of the Methylthioxylose Capping Motif of Lipoarabinomannan in Mycobacterium tuberculosis
    Angala, Shiva Kumar
    McNeil, Michael R.
    Shi, Libin
    Joe, Maju
    Pham, Ha
    Zuberogoitia, Sophie
    Nigou, Jerome
    Boot, Claudia M.
    Lowary, Todd L.
    Gilleron, Martine
    Jackson, Mary
    ACS CHEMICAL BIOLOGY, 2017, 12 (03) : 682 - 691
  • [4] Asymmetric synthesis and structure elucidation of a glycerophospholipid from Mycobacterium tuberculosis
    ter Horst, Bjorn
    Seshadri, Chetan
    Sweet, Lindsay
    Young, David C.
    Feringa, Ben L.
    Moody, D. Branch
    Minnaard, Adriaan J.
    JOURNAL OF LIPID RESEARCH, 2010, 51 (05) : 1017 - 1022
  • [5] Identification of the monocyte activating motif in Mycobacterium tuberculosis chaperonin 60.1
    Hu, Yanmin
    Coates, Anthony R. M.
    Liu, Alexander
    Lund, Peter A.
    Henderson, Brian
    TUBERCULOSIS, 2013, 93 (04) : 442 - 447
  • [6] Deciphering the essentiality and function of SxSx motif in Mycobacterium tuberculosis UvrB
    Thakur, Manoj
    Muniyappa, K.
    BIOCHIMIE, 2020, 170 : 94 - 105
  • [7] Unusual Conformation of the SxN Motif in the Crystal Structure of Penicillin-Binding Protein A from Mycobacterium tuberculosis
    Fedarovich, Alena
    Nicholas, Robert A.
    Davies, Christopher
    JOURNAL OF MOLECULAR BIOLOGY, 2010, 398 (01) : 54 - 65
  • [8] Crystallization and structure analysis of the core motif of the Pks13 acyltransferase domain from Mycobacterium tuberculosis
    Yu, Mingjing
    Dou, Chao
    Gu, Yijun
    Cheng, Wei
    PEERJ, 2018, 6
  • [9] [Au]/[Ag]-catalysed expedient synthesis of branched heneicosafuranosyl arabinogalactan motif of Mycobacterium tuberculosis cell wall
    Shivaji A. Thadke
    Bijoyananda Mishra
    Maidul Islam
    Sandip Pasari
    Sujit Manmode
    Boddu Venkateswara Rao
    Mahesh Neralkar
    Ganesh P. Shinde
    Gulab Walke
    Srinivas Hotha
    Nature Communications, 8
  • [10] [Au]/[Ag]-catalysed expedient synthesis of branched heneicosafuranosyl arabinogalactan motif of Mycobacterium tuberculosis cell wall
    Thadke, Shivaji A.
    Mishra, Bijoyananda
    Islam, Maidul
    Pasari, Sandip
    Manmode, Sujit
    Rao, Boddu Venkateswara
    Neralkar, Mahesh
    Shinde, Ganesh P.
    Walke, Gulab
    Hotha, Srinivas
    NATURE COMMUNICATIONS, 2017, 8