Laser-induced acoustic desorption

被引:79
|
作者
Golovlev, VV [1 ]
Allman, SL [1 ]
Garrett, WR [1 ]
Taranenko, NI [1 ]
Chen, CH [1 ]
机构
[1] Oak Ridge Natl Lab, Div Life Sci, Oak Ridge, TN 37831 USA
关键词
biomolecular mass analysis; laser-induced acoustic desorption; MALDI;
D O I
10.1016/S0168-1176(97)00209-7
中图分类号
O64 [物理化学(理论化学)、化学物理学]; O56 [分子物理学、原子物理学];
学科分类号
070203 ; 070304 ; 081704 ; 1406 ;
摘要
The basic principles and experimental results of laser-induced acoustic desorption (LIAD) are reported in this work. LIAD was successfully used to desorb biomolecules in a mass spectrometer. LIAD holds some promise to eliminate many key factors which contribute to poor mass resolution in MALDI. Thus, it has potential for improvement in resolution of biomolecular mass analysis. (C) 1997 Elsevier Science B.V.
引用
收藏
页码:69 / 78
页数:10
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