Pt(II)-catalyzed synthesis of 1,2-dihydropyridines from aziridinyl propargylic esters

被引：43

作者：

Motamed, Massoud ^{[1
]}

Bunnelle, Eric M. ^{[1
]}

Singaram, Surendra W. ^{[1
]}

Sarpong, Richmond ^{[1
]}

机构：

[1] Univ Calif Berkeley, Dept Chem, Berkeley, CA 94720 USA

来源：

ORGANIC LETTERS | 2007年 / 9卷 / 11期

关键词：

D O I：

10.1021/ol070658i

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Pt(II)-catalyzed cycloisomerization of aziridinyl propargylic esters affords 1,2-dihydropyridines with regiodefined installation of substituents. A mild conversion of the 1,2-dihydropyridines to the corresponding substituted pyridines as well as chirality retention from the aziridinyl propargylic ester substrates have been demonstrated.

引用

页码：2167 / 2170

页数：4

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