Reducing perioperative blood loss with antifibrinolytics and antifibrinolytic-like agents for patients undergoing total hip and total knee arthroplasty

被引：10

作者：

Kapadia, Bhaveen H. ^{[1
]}

Torre, Barrett B. ^{[1
]}

Ullman, Nicholas ^{[1
,2
]}

Yang, Andrew ^{[1
]}

Harb, Matthew A. ^{[1
]}

Grieco, Preston W. ^{[1
]}

Newman, Jared M. ^{[1
]}

Harwin, Steven F. ^{[3
]}

Maheshwari, Aditya, V ^{[1
]}

机构：

[1] Suny Downstate Med Ctr, Dept Orthopaed Surg, Brooklyn, NY 11203 USA

[2] Univ Rochester, Dept Surg, Sch Med & Dent, Rochester, NY USA

[3] Icahn Sch Med Mt Sinai, Leni & Peter W May Dept Orthopaed, New York, NY 10029 USA

来源：

JOURNAL OF ORTHOPAEDICS | 2019年 / 16卷 / 06期

关键词：

Antifibrinolytic; Tranexamic acid; Aminocaproic acid; Fibrin tissue adhesive; Aprotinin; Total joint arthroplasty; EPSILON-AMINOCAPROIC ACID; MAJOR ORTHOPEDIC-SURGERY; TRANEXAMIC ACID; FIBRIN SEALANT; APROTININ; TRANSFUSION; REPLACEMENT; ANESTHESIA; REDUCTION; SAFETY;

D O I：

10.1016/j.jor.2019.06.025

中图分类号：

R826.8 [整形外科学]; R782.2 [口腔颌面部整形外科学]; R726.2 [小儿整形外科学]; R62 [整形外科学（修复外科学）];

学科分类号：

摘要：

Total hip and knee arthroplasties may be associated with a significant amount of perioperative blood loss. The severity of blood loss may be great enough to require the use of blood transfusions to treat perioperative anemia. Various methods of blood preservation have been studied. The use of antifibrinolytics and antifibrinolytic-like agents to reduce perioperative bleeding has been researched in orthopaedics and other surgical subspecialties. This review aims to evaluate the current evidence supporting the use of tranexamic acid, aminocaproic acid, fibrin tissue adhesive, and aprotinin in the reduction of perioperative blood loss in total hip and knee arthroplasties.

引用

页码：513 / 516

页数：4

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