The Study on the Antibacterial Activity of Compounds from the Isodon Species

被引:5
|
作者
Isobe, Takahiko [1 ]
Nagata, Kumiko [2 ]
机构
[1] Hyogo Univ Hlth Sci, Dept Chem, Liberal Arts Ctr, Chuo Ku, Kobe, Hyogo 6508530, Japan
[2] Senri Kinran Univ, Dept Food & Nutr, Fac Human Life Sci, Osaka 5650873, Japan
关键词
antibiotic activity; Isodon; isodocarpin; Rabdosia; oridonin; HELICOBACTER-PYLORI; CHEMICAL-CONSTITUENTS; RABDOSIA-TRICHOCARPA; DITERPENOIDS; COMPONENTS; ANTITUMOR; LABIATAE; JAPONICA; LEAVES; PLANTS;
D O I
10.1248/yakushi.130.447
中图分类号
R9 [药学];
学科分类号
1007 ;
摘要
We investigated antibacterial activities of ten compounds from Isodon species against five strains of Escherichia coli, Staphylococcus epidermidis, Serratia marcescens, Streptococcus mutans, and Helicobacterpylori. The compounds with the MIC values of 25 mu g/ml were isodocarpin against Sta. epidermidis, Str. mutans, and H. pylori, nodosin against Sta. epidermidis and Str. mutans, oridonin against Ser. marcescens, and pedalitin. against H. pylori.
引用
收藏
页码:447 / 450
页数:4
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