Exploration of GO-CuO nanocomposite for its antibacterial properties and potential application as a chemosensor in the sensing of L-Leucine

Graphene known as the wonder material and finds its utilization in various applications including sensors.This work reports the solvothermal route and the chemical reflux method synthesis of graphene oxide copper oxide nanocomposite material (GO-CuO). The hitherto prepared GO-CuO nanocomposite was well characterized using the usual spectroscopic and microscopic technique such as Fourier transform infrared (FTIR) spectroscopy, Scanning electron microscopy (SEM), X-ray diffraction (XRD), UV-Vis Spectroscopy (UV), Photoluminescence Spectroscopy(PL) etc. The prepared GO-CuO nanocomposite was found to selectively bind to L-Leucine without any interference from the other naturally occurring L-amino acids as a potential fluorescent chemosensor. The interference studies, effect of time, effect of pH and various equivalence studies were also performed for the GO-CuO nanocomposite with L-Leucine. The antibacterial activity of GO-CuO nanocomposite revealed a minimum inhibitory zone concentration for Methicillin Resistant Staphylococcus aureus to be 200 mu g/ml, whereas for A. baumannii it was found to be 100 mu g/ml.