Meniere's disease;
clinical subtyping;
genetics;
big data;
ENDOLYMPHATIC HYDROPS;
GENETIC-HETEROGENEITY;
D O I:
10.1177/0194599818773077
中图分类号:
R76 [耳鼻咽喉科学];
学科分类号:
100213 ;
摘要:
Fundamentally, Meniere's disease is a constellation of symptoms and, as such, may represent the final common pathway for a number of disease processes, as opposed to being the consequence of a single isolated pathology. Within this type of consideration, much can be learned regarding the etiology, presentation, prognosis, and treatment of these individual conditions by applying subtyping techniques currently employed to better understand similar disease processes that are encountered in other allied fields of medicine. This commentary proposes the principles, required processes, and benefits of subtyping for Meniere's disease.