Aspirin for the Prevention of Preeclampsia and Intrauterine Growth Restriction

被引：33
|
作者：
Roberge, Stephanie [1 ]
Odibo, Anthony O. [2 ]
Bujold, Emmanuel [1 ,3 ]
机构：
[1] Univ Laval, Fac Med, Dept Social & Prevent Med, 2705 Blvd Laurier, Quebec City, PQ G1V 4G2, Canada
[2] Univ S Florida, Morsani Coll Med, Dept Obstet & Gynecol, Div Maternal Fetal Med, 2 Tampa Gen Circle,6th Floor, Tampa, FL 33606 USA
[3] Univ Laval, Fac Med, Dept Obstet & Gynecol, 2705 Blvd Laurier, Quebec City, PQ G1V 4G2, Canada
来源：
CLINICS IN LABORATORY MEDICINE | 2016年 / 36卷 / 02期
关键词：
Pregnancy; Preeclampsia; Intrauterine growth restriction; Aspirin; Placenta; LOW-DOSE ASPIRIN; UTERINE ARTERY DOPPLER; EARLY-ONSET PREECLAMPSIA; HIGH-RISK WOMEN; PREGNANT-WOMEN; PHYSIOLOGICAL TRANSFORMATION; TROPHOBLASTIC INVASION; ACETYLSALICYLIC-ACID; SPIRAL ARTERIES; PLACENTAL BED;
D O I：
10.1016/j.cll.2016.01.013
中图分类号：
R446 [实验室诊断]; R-33 [实验医学、医学实验];
学科分类号：
1001 ;
摘要：
Low-dose aspirin (LDA) has been used for several years for the prevention of preeclampsia (PE). LDA started in early pregnancy is associated with improvement of placental implantation. The best evidence suggests that LDA can prevent more than half of PE cases in high-risk women when started before 16 weeks of gestation. Moreover, LDA started in early pregnancy reduces the risk of other placenta mediated complications such as intrauterine growth restriction (IUGR) and perinatal death. The efficacy of LDA has been demonstrated in women with abnormal first-trimester uterine artery Doppler or with prior history of chronic hypertension or preeclampsia.
引用
收藏
页码：319 / +
页数：12
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