Development of Biomimetic Chitosan-Based Hydrogels Using an Elastin-Like Polymer

被引：17
|
作者：
Barbosa, Joaquim S. [1 ]
Ribeiro, Artur [3 ]
Testera, Ana M. [3 ]
Alonso, Matilde [3 ]
Arias, Francisco J. [3 ]
Rodriguez-Cabello, Jose C. [2 ,3 ]
Mano, Joao F. [1 ]
机构：
[1] 3Bs Res Grp Biomat Biodegradables & Biomimet, P-4806909 Caldas Das Taipas, Guimaraes, Portugal
[2] Univ Valladolid, GIR Bioforge, E-47011 Valladolid, Spain
[3] Networking Res Ctr Bioengn Biomat & Nanomed CIBER, Valladolid, Spain
来源：
ADVANCED ENGINEERING MATERIALS | 2010年 / 12卷 / 1-2期
关键词：
IN-VITRO CHARACTERIZATION; ALTERNATE SOAKING PROCESS; BIOMEDICAL APPLICATIONS; CONTROLLED-RELEASE; SCAFFOLD DESIGN; BONE; TEMPERATURE; CARTILAGE; MATRICES; SYSTEMS;
D O I：
10.1002/adem.200980152
中图分类号：
T [工业技术];
学科分类号：
08 ;
摘要：
Chitosan and an elastin-like polymer, containing a specific osteoconductive sequence in the primary structure, have been combined to obtain bioactive injectable systems with enhanced mechanical properties and hydrogels. Obtained results indicate that the combination of such polymers may be very promising in the development of biomaterials for minimal invasive orthopaedic reconstructive applications or in bone tissue engineering. The figure shows a thermo-sensitive hydrogel, with a gelation point under physiological temperature. © 2010 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.
引用
收藏
页码：B37 / B44
页数：8
相关论文
共 50 条
  • [21] Development of Injectable Thermosensitive Chitosan-Based Hydrogels for Cell Encapsulation
    Stanzione, Antonella
    Polini, Alessandro
    La Pesa, Velia
    Romano, Alessandro
    Quattrini, Angelo
    Gigli, Giuseppe
    Moroni, Lorenzo
    Gervaso, Francesca
    APPLIED SCIENCES-BASEL, 2020, 10 (18):
  • [22] Thermoswitchable Nanoparticles Based on Elastin-like Polypeptides
    Kracke, Bettina
    Cole, James T.
    Kaiser, Christoph J. O.
    Hellenkamp, Bjoern
    Krysiak, Stefanie
    Ghoorchian, Ali
    Braun, Gary B.
    Holland, Nolan B.
    Hugel, Thorsten
    MACROMOLECULES, 2015, 48 (16) : 5868 - 5877
  • [23] Elastin-Like Polypeptide Based Hydroxyapatite Bionanocomposites
    Wang, Eddie
    Lee, Sang-Hyuk
    Lee, Seung-Wuk
    BIOMACROMOLECULES, 2011, 12 (03) : 672 - 680
  • [24] Recovery of levansucrase using elastin-like polypeptides
    Kang, HJ
    Kim, JH
    Kim, ES
    Koo, YM
    FRONTIERS ON SEPARATION SCIENCE AND TECHNOLOGY, 2004, : 758 - 763
  • [25] 3D microstructuring of smart bioactive hydrogels based on recombinant elastin-like polymers
    Martin, Laura
    Alonso, Matilde
    Moeller, Martin
    Rodriguez-Cabello, Jose Carlos
    Mela, Petra
    SOFT MATTER, 2009, 5 (08) : 1591 - 1593
  • [26] Synthesis and characterization of matrix metalo-protease-sensitive Elastin-like based bioactive hydrogels
    Girotti, A.
    Vallejo, F. J. Arias
    Alonso, M.
    Testera, A. M.
    Cabello, J. C. Rodriguez
    TISSUE ENGINEERING PART A, 2008, 14 (05) : 783 - 784
  • [27] Chitosan-based hydrogels as biomaterials.
    Dumitriu, S
    Chornet, E
    ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 1997, 213 : 128 - CELL
  • [28] Synthesis and characterization of chitosan-based hydrogels
    Li, Qianzhu
    Yang, Dongzhi
    Ma, Guiping
    Xu, Qiang
    Chen, Xiangmei
    Lu, Fengmin
    Nie, Jun
    INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES, 2009, 44 (02) : 121 - 127
  • [29] Cylindrical Polymer Brushes with Elastin-Like Polypeptide Side Chains
    Weller, Desiree
    McDaniel, Jonathan R.
    Fischer, Karl
    Chilkoti, Ashutosh
    Schmidt, Manfred
    MACROMOLECULES, 2013, 46 (12) : 4966 - 4971
  • [30] Chitosan-based hydrogels: Synthesis and characterization
    Borzacchiello, A
    Ambrosio, L
    Netti, PA
    Nicolais, L
    Peniche, C
    Gallardo, A
    San Roman, J
    JOURNAL OF MATERIALS SCIENCE-MATERIALS IN MEDICINE, 2001, 12 (10-12) : 861 - 864
12345