Trends in antimicrobial non-susceptibility in methicillin-resistant Staphylococcus aureus from Germany (2004-2011)

被引:10
|
作者
Schaumburg, F. [1 ]
Idelevich, E. A. [1 ]
Peters, G. [1 ]
Mellmann, A. [2 ]
von Eiff, C. [1 ,3 ]
Becker, K. [1 ]
机构
[1] Univ Hosp Munster, Inst Med Microbiol, D-48149 Munster, Germany
[2] Univ Hosp Munster, Inst Hyg, D-48149 Munster, Germany
[3] Pfizer Pharma GmbH, Berlin, Germany
关键词
Genotype; Germany; LA-MRSA; methicillin-resistant Staphylococcus aureus; resistance; MRSA; LIVESTOCK;
D O I
10.1111/1469-0691.12519
中图分类号
R51 [传染病];
学科分类号
100401 ;
摘要
We analysed trends in antimicrobial non-susceptibility in methicillin-resistant Staphylococcus aureus (MSRA) from Germany to assess the impact of the changing population structure of MRSA on antimicrobial resistance rates. During two large nationwide multicentre studies in 2004-2005 and 2010-2011, we collected consecutively spa-genotyped MRSA isolates. The increase in non-susceptibility rates for tetracycline and trimethoprim-sulphamethoxazole was associated with the spread of livestock-associated MRSA. A decrease in non-susceptibility rates for aminoglycosides and quinolones affected all major lineages (spa-clonal complexes003, 008, and 032). All isolated remained susceptible to glycopeptides and linezolid.
引用
收藏
页码:O554 / O557
页数:4
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