MGD: the Mouse Genome Database

被引:184
|
作者
Blake, JA [1 ]
Richardson, JE [1 ]
Bult, RJ [1 ]
Kadin, JA [1 ]
Eppig, JT [1 ]
机构
[1] Jackson Lab, Bar Harbor, ME 04609 USA
关键词
D O I
10.1093/nar/gkg047
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
The Mouse Genome Database (MGD) (http://www.informatics.jax.org) one component of community database resource for the laboratory mouse, key model organism for interpreting the human genome and for understanding human biology. MGD strives to provide an extensively integrated information resource with experimental details annotated from both literature and on-line genomic data sources. MGD curates and presents the consensus representation of genotype (sequence) to phenotype information including highly detailed information about genes and gene products. Primary foci of integration are through representations of relationships between genes, sequences and phenotypes. MGD collaborates with other bioinformatics groups to curate definitive set of information about the laboratory mouse. Recent developments include general implementation of database structures for controlled vocabularies and the integration of phenotype classification system.
引用
收藏
页码:193 / 195
页数:3
相关论文
共 50 条
  • [31] Orthology for comparative genomics in the mouse genome database
    Dolan, Mary E.
    Baldarelli, Richard M.
    Bello, Susan M.
    Ni, Li
    McAndrews, Monica S.
    Bult, Carol J.
    Kadin, James A.
    Richardson, Joel E.
    Ringwald, Martin
    Eppig, Janan T.
    Blake, Judith A.
    MAMMALIAN GENOME, 2015, 26 (7-8) : 305 - 313
  • [32] The Mouse Genome Database: A tool for comparative genomics
    Drabkin, HJ
    Blake, JA
    Bult, CJ
    Richardson, JE
    Kadin, JA
    Eppig, JT
    FASEB JOURNAL, 2001, 15 (05): : A724 - A724
  • [33] Orthology for comparative genomics in the mouse genome database
    Mary E. Dolan
    Richard M. Baldarelli
    Susan M. Bello
    Li Ni
    Monica S. McAndrews
    Carol J. Bult
    James A. Kadin
    Joel E. Richardson
    Martin Ringwald
    Janan T. Eppig
    Judith A. Blake
    Mammalian Genome, 2015, 26 : 305 - 313
  • [34] The Mouse Genome Database: integration of and access to knowledge about the laboratory mouse
    Blake, Judith A.
    Bult, Carol J.
    Eppig, Janan T.
    Kadin, James A.
    Richardson, Joel E.
    NUCLEIC ACIDS RESEARCH, 2014, 42 (D1) : D810 - D817
  • [35] Mouse Genome Database: Curation strategies for alleles and phenotypes in the mouse.
    Smith, CL
    Blake, JA
    Richardson, JE
    Kadin, JA
    Eppig, JT
    AMERICAN JOURNAL OF HUMAN GENETICS, 2001, 69 (04) : 450 - 450
  • [36] dbSUPER: a database of super-enhancers in mouse and human genome
    Khan, Aziz
    Zhang, Xuegong
    NUCLEIC ACIDS RESEARCH, 2016, 44 (D1) : D164 - D171
  • [37] A genome-wide and nonredundant mouse transcription factor database
    Kanamori, M
    Konno, H
    Osato, N
    Kawai, J
    Hayashizaki, Y
    Suzuki, H
    BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 2004, 322 (03) : 787 - 793
  • [38] The Mouse Genome Database: Genotypes, Phenotypes, and Models of Human Disease
    Bult, Carol J.
    Eppig, Janan T.
    Blake, Judith A.
    Kadin, James A.
    Richardson, Joel E.
    NUCLEIC ACIDS RESEARCH, 2013, 41 (D1) : D885 - D891
  • [39] Mouse Genome Database: From sequence to phenotypes and disease models
    Eppig, Janan T.
    Richardson, Joel E.
    Kadin, James A.
    Smith, Cynthia L.
    Blake, Judith A.
    Bult, Carol J.
    GENESIS, 2015, 53 (08) : 458 - 473
  • [40] Integrating computationally assembled mouse transcript sequences with the Mouse Genome Informatics (MGI) database
    Yunxia Zhu
    Benjamin L King
    Babak Parvizi
    Brian P Brunk
    Christian J Stoeckert
    John Quackenbush
    Joel Richardson
    Carol J Bult
    Genome Biology, 4