Effectiveness of COVID-19 vaccines in preventing SARS-CoV-2 infection and hospitalisation, Navarre, Spain, January to April 2021

被引：62
|
作者：
Martinez-Baz, Ivan [1 ,2 ,3 ]
Miqueleiz, Ana [3 ,4 ]
Casado, Itziar [1 ,2 ,3 ]
Navascues, Ana [3 ,4 ]
Trobajo-Sanmartin, Camino [3 ,4 ]
Burgui, Cristina [1 ,2 ,3 ]
Guevara, Marcela [1 ,2 ,3 ]
Ezpeleta, Carmen [3 ,4 ]
Castilla, Jesus [1 ,2 ,3 ]
机构：
[1] Inst Salud Publ Navarra, Pamplona, Spain
[2] CIBER Epidemiol & Salud Publ CIBERESP, Madrid, Spain
[3] Navarra Inst Hlth Res IdiSNA, Pamplona, Spain
[4] Complejo Hosp Navarra, Dept Clin Microbiol, Pamplona, Spain
来源：
EUROSURVEILLANCE | 2021年 / 26卷 / 21期
基金：
欧盟地平线“2020”;
关键词：
D O I：
10.2807/1560-7917.ES.2021.26.21.2100438
中图分类号：
R51 [传染病];
学科分类号：
100401 ;
摘要：
COVID-19 vaccine effectiveness was evaluated in close contacts of cases diagnosed during January-April 2021. Among 20,961 contacts, 7,240 SARS-CoV-2 infections were confirmed, with 5,467 being symptomatic and 559 leading to hospitalisations. Non-brand-specific one and two dose vaccine effectiveness were respectively, 35% (95% confidence interval (CI): 25 to 44) and 66% (95% CI: 57 to 74) against infections, 42% (95% CI: 31 to 52) and 82% (95% CI: 74 to 88) against symptomatic infection, and 72% (95% CI: 47 to 85) and 95% (95% CI: 62 to 99) against COVID-19 hospitalisation. The second dose significantly increased effectiveness. Findings support continuing complete vaccination.
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页数：7
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