Rapid Access to Indeno[1,2-c] quinolines via Bronsted Acid-Catalyzed Cascade Reaction

被引：8
|
作者：
Boominathan, Siva Senthil Kumar [1 ]
Wang, Jeh-Jeng [1 ,2 ]
机构：
[1] Kaohsiung Med Univ, Dept Med & Appl Chem, 100 Shiquan Ist Rd, Kaohsiung 807, Taiwan
[2] Kaohsiung Med Univ Hosp, Dept Med Res, 100 Tzyou Ist Rd, Kaohsiung 807, Taiwan
来源：
ADVANCED SYNTHESIS & CATALYSIS | 2017年 / 359卷 / 11期
关键词：
alkynes; Bronsted acid catalysis; cascade reaction; indeno[1,2-c] quinolines; polycyclic heterocycles; DERIVATIVES; CYCLIZATION; BENZOFURANS; INHIBITORS; DISCOVERY;
D O I：
10.1002/adsc.201700190
中图分类号：
O69 [应用化学];
学科分类号：
081704 ;
摘要：
A Bronsted acid-catalyzed annulation strategy has been developed to construct indeno[1,2-c] quinolines. This tandem synthetic method proceeds through a sequential electrophilic addition followed by a Friedel-Crafts-type reaction. A variety of tetracyclic compounds was obtained in moderate to high yields under mild reaction conditions in a short time.
引用
收藏
页码：1844 / 1848
页数：5
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