A new type of water-soluble fluorescent boronic acid suitable for construction of polyboronic acids for carbohydrate recognition

被引：4
|
作者：
Yang, WQ
Li, L
Wang, BH
机构：
[1] N Carolina State Univ, Dept Chem, Raleigh, NC 27695 USA
[2] Georgia State Univ, Dept Chem, Atlanta, GA 30303 USA
来源：
HETEROCYCLIC COMMUNICATIONS | 2004年 / 10卷 / 06期
关键词：
D O I：
暂无
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
In this paper we report boronic acid 1 with a quinoline moiety as a new type of fluorescent probe for carbohydrates, which shows significant fluorescence intensity increases upon sugar binding at physiological pH. This compound has the unique structural feature of separating the boronic acid moiety from the presumed fluorophore, and is ready for the construction of polyboronic acids through tethering to its carboxylic group for high selectivity and affinity recognition of carbohydrates of biological interest.
引用
收藏
页码：383 / 388
页数：6
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