Cancer biology: Messages in extracellular vesicles depend on centrosome number

被引：1
|
作者：
Jewett, Cayla E. [1 ]
Pearson, Chad G. [1 ]
机构：
[1] Univ Colorado, Dept Cell & Dev Biol, Anschutz Med Campus, Aurora, CO 80045 USA
来源：
CURRENT BIOLOGY | 2021年 / 31卷 / 07期
关键词：
EXTRA CENTROSOMES; CELLS; MECHANISM; P53;
D O I：
10.1016/j.cub.2021.01.057
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
Extra centrosomes are linked to cancer-associated errors in cell division, metastasis and signaling. A new study reveals that centrosome amplification disrupts lysosome function, leading to the release of small extracellular vesicles and to invasive activity in pancreatic cells.
引用
收藏
页码：R337 / R340
页数：4
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