Linkage mapping of rat chromosome markers generated from chromosome-sorted DNA

被引：8
|
作者：
Deng, AY
Smith-Mensah, WH
Hoebee, B
Garrett, M
Rapp, JP
机构：
[1] Med Coll Ohio, Dept Physiol & Mol Med, Toledo, OH 43699 USA
[2] Med Coll Ohio, Dept Surg, Toledo, OH 43699 USA
[3] Natl Inst Publ Hlth & Environm, Hlth Effects Res Lab, NL-3720 RA Bilthoven, Netherlands
来源：
MAMMALIAN GENOME | 1998年 / 9卷 / 01期
关键词：
D O I：
10.1007/s003359900676
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
Ninety-one new rat microsatellite chromosome markers were generated through screening chromosome-sorted DNA libraries. Of the 91 markers, 29 have been mapped to various rat chromosomes. Because of a lack of suitable polymorphisms among the appropriate rat strains of our interest, the remaining 62 markers are still unassigned, but are likely to be useful for genotyping different rat strains employed to study a wide range of genetic traits other than blood pressure. With these new markers, two genes, encoding or, adrenergic receptor, class II and gastric H,K-ATPase beta subunit, were mapped to regions on rat Chromosomes (Chrs) 1 and 16 respectively.
引用
收藏
页码：38 / 43
页数：6
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