Improved synthesis of chalcones and pyrazolines under ultrasonic irradiation

被引：0

作者：

Gupta, Ragini ^{[1
]}

Gupta, Neetu ^{[2
]}

Jain, Anshu ^{[1
]}

机构：

[1] Malaviya Natl Inst Technol, Dept Chem, Jaipur 302017, Rajasthan, India

[2] Univ Rajasthan, Dept Chem, Ctr Adv Studies, Jaipur 302004, Rajasthan, India

来源：

INDIAN JOURNAL OF CHEMISTRY SECTION B-ORGANIC CHEMISTRY INCLUDING MEDICINAL CHEMISTRY | 2010年 / 49卷 / 03期

关键词：

Chalcones; 2-pyrazolines; Claisen-Schmidt condensation; sonochemistry; antimicrobial; 2-PYRAZOLINES;

D O I：

暂无

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Five 1,3-diarylprop-2-en-1-ones 3a-e are synthesized by Claisen-Schmidt condensation of aryl methyl ketones and 4-chlorobenzaldehyde to give pyrazolines 5a-e by cyclization with phenylhydrazine in gl. acetic acid using ultrasonic irradiation. in lesser time with higher yields. All the synthesized compounds are characterized by elemental analyses and spectral data IR. PMR and are screened for their antimicrobial activities. Some of them have shown promising results against E. coli, S. aureus, C. albicans and A. niger.

引用

页码：351 / 355

页数：5

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