Investigation of the free volume in olanzapine by PALS

被引:3
|
作者
Jasinska, B. [1 ]
Kedzior, M. [1 ]
Sniegocka, M. [2 ]
Koziol, A. E. [2 ]
Wawrzycka-Gorczyca, I. [2 ]
机构
[1] Marie Curie Sklodowska Univ, Inst Phys, Pl Marii Curie Sklodowskiej 1, PL-20031 Lublin, Poland
[2] Marie Curie Sklodowska Univ, Fac Chem, Pl Marii Curie Sklodowskiej 1, PL-20031 Lublin, Poland
关键词
LIFETIMES;
D O I
10.1002/pssc.200982110
中图分类号
T [工业技术];
学科分类号
08 ;
摘要
Two polymorphic forms of olanzapine were investigated as a function of temperature in a range from 100 to 420 K and as a function of hydrostatic pressure from 0 to 1300 MPa using positron annihilation lifetime spectroscopy. In the crystallographic structure of both investigated forms exists component ascribed to positronium formation. The lifetime value of o-Ps changes nonmonotinicaly from 1.0 to 1.6 ns as a function of temperature. (C) 2009 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim
引用
收藏
页码:2432 / +
页数:2
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