Spectrophotometric determination of flutamide in pharmaceutical formulation

被引:0
|
作者
Rao, GD [1 ]
机构
[1] KVSR Siddhartha Coll Pharmaceut Sci, Dept Pharmaceut Chem, Vijayawada 520010, India
关键词
spectrophotometric determination; flutamide; pharmaceutical formulation;
D O I
暂无
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
Two simple, sensitive and precise spectrophotometric methods (Method A and Method B) are developed for the determination of flutamide (FMD) in pure and dosage forms. These methods are based on the formation of coloured species on treatment of reduced FMD with 1,10-phenanthroline and Fe(III) [Method A] and diazotization followed by coupling with alpha-naphthylamine [Method B].
引用
收藏
页码:1769 / 1772
页数:4
相关论文
共 50 条
  • [41] DEVELOPMENT AND VALIDATION OF SPECTROPHOTOMETRIC METHOD FOR THE DETERMINATION OF RISPERIDONE IN BULK DRUG AND PHARMACEUTICAL FORMULATION
    Hasan, Moynul
    Al Masud, Abdullh
    Ahmed, Jamiuddin
    INTERNATIONAL JOURNAL OF PHARMACEUTICAL SCIENCES AND RESEARCH, 2011, 2 (02): : 378 - 382
  • [42] Determination of levofloxacin in a pharmaceutical injectable formulation by using HPLC and UV spectrophotometric methods
    Hurtado, Felipe Kellermann
    Nogueira, Daniele Rubert
    Bortolini, Fernanda
    da Silva, Luclia Magalhes
    Zimmermann, Estevan
    Jost e Souza, Marines
    de Melo, Janine
    Bueno Rolim, Clarice Madalena
    JOURNAL OF LIQUID CHROMATOGRAPHY & RELATED TECHNOLOGIES, 2007, 30 (13-16) : 1981 - 1989
  • [43] Development and validation of derivative spectrophotometric method for determination of rabeprazole sodium in pharmaceutical formulation
    Garcia, CV
    Sippel, J
    Steppe, M
    Schapoval, EES
    ANALYTICAL LETTERS, 2006, 39 (02) : 341 - 348
  • [44] Spectrophotometric Determination of Chloroquine, Pyrimethamine and Trimethoprim by Ion Pair Extraction in Pharmaceutical Formulation and Urine
    Nagaraja, Padmarajaiah
    Shrestha, Ashwinee Kumar
    Shivakumar, Anantharaman
    Gowda, Avinash K.
    JOURNAL OF FOOD AND DRUG ANALYSIS, 2010, 18 (04) : 239 - 248
  • [45] Spectrophotometric Methods for Simultaneous Determination of Oxytetracycline HCl and Flunixin Meglumine in Their Veterinary Pharmaceutical Formulation
    Merey, Hanan A.
    Abd-Elmonem, Mahmmoud S.
    Nazlawy, Hagar N.
    Zaazaa, Hala E.
    JOURNAL OF ANALYTICAL METHODS IN CHEMISTRY, 2017, 2017
  • [46] Spectrophotometric Method for Determination of Methyldopa in Bure and Pharmaceutical Formulation Based on Oxidative Coupling Reaction
    Shakkor, Shahla Jamal
    Mohammed, Nabeel
    Shakor, Safaa Ridha
    CHEMICAL METHODOLOGIES, 2022, 6 (11): : 851 - 860
  • [47] A Direct Spectrophotometric Method for Determination of Antiparasitic Drug Nitazoxanide in a Bulk Form and Pharmaceutical Formulation
    El-desoky, Hanaa S.
    Ghoneim, Mohamed M.
    Abdel-Galeil, Mohamed M.
    CHEMIA ANALITYCZNA, 2009, 54 (05): : 1065 - 1077
  • [48] Determination of Tolterodine Via Ion Pair Complex Using Spectrophotometric Method in Pharmaceutical Formulation
    Ibrahim, Munjed M.
    Alarjah, Mohammed
    CURRENT PHARMACEUTICAL ANALYSIS, 2018, 14 (04) : 367 - 372
  • [49] Validated Spectrophotometric Methods for Simultaneous Determination of Atorvastatin Calcium and Olmesartan Medoxomil in Their Pharmaceutical Formulation
    Kamal, Amira H.
    Hammad, Sherin F.
    Marie, Aya A.
    JOURNAL OF AOAC INTERNATIONAL, 2022, 105 (02) : 387 - 395
  • [50] Application of Charge Transfer Reactions for the Quantitative Spectrophotometric Determination of Cyclophosphamide in Pure and Pharmaceutical Formulation
    Siddappa, K.
    Hanamshetty, Prashant C.
    CURRENT PHARMACEUTICAL ANALYSIS, 2015, 11 (02) : 131 - 138