Effect of alcoholic intoxication on water content and activity of Na,K-ATPase and Ca-ATPase in rat brain

被引：7
|
作者：
Zamai, TN [1 ]
Titova, NM [1 ]
Zamai, AS [1 ]
Usol'tseva, OS [1 ]
Yulenkova, OV [1 ]
Shumkova, AA [1 ]
机构：
[1] Krasnoyarsk State Univ, Dept Human & Anim Biochem & Physiol, Krasnoyarsk, Russia
来源：
BULLETIN OF EXPERIMENTAL BIOLOGY AND MEDICINE | 2002年 / 134卷 / 06期
关键词：
alcohol intoxication; brain; Na; K-ATPase; Ca-ATPase; malonic dialdehyde;
D O I：
10.1023/A:1022948709336
中图分类号：
R-3 [医学研究方法]; R3 [基础医学];
学科分类号：
1001 ;
摘要：
We studied the effect of 2-week alcohol intoxication on water exchange and activity of Na,K-ATPase and Ca-ATPase in rat brain. Alcohol intoxication increased water content in the brain due to cell hyperhydration. It is assumed that hyperhydration results from increased Na+ content in cells due to inhibition Na,K-ATPase activity, which in turn is caused by activation of lipid peroxidation under the effect of ethanol. A possible mechanism of Na,K-ATPase inhibition.
引用
收藏
页码：541 / 543
页数：3
相关论文
共 50 条
  • [31] EFFECT OF ACETYLCHOLINE ON NA,K-ATPASE ACTIVITY OF RAT SPLEEN AND LYMPHOSARCOMA HOMOGENATES
    MUSTAFIN, AM
    SEITKAZINA, GD
    BULLETIN OF EXPERIMENTAL BIOLOGY AND MEDICINE, 1981, 91 (06) : 794 - 795
  • [32] ELECTROPHORETIC SEPARATION OF DIFFERENT PHOSPHOPROTEINS ASSOCIATED WITH CA-ATPASE AND NA,K-ATPASE IN HUMAN RED-CELL GHOSTS
    KNAUF, PA
    PROVERBIO, F
    HOFFMAN, JF
    JOURNAL OF GENERAL PHYSIOLOGY, 1974, 63 (03): : 324 - 336
  • [33] ADAPTATION OF BRAIN NA,K-ATPASE TO CHANGES IN NEURAL ACTIVITY
    SWANN, AC
    JOURNAL OF GENERAL PHYSIOLOGY, 1990, 96 (06): : A85 - A85
  • [34] Na,K-ATPase and Ca-ATPase activities of the myocardial sarcolemma in aging rats after aorta coarctation: Role of invertors
    Frolkis, VV
    Kobzar, AL
    Pugach, BV
    GERONTOLOGY, 1999, 45 (04) : 184 - 186
  • [35] ANTIBODIES IN COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY - A STUDY OF KIDNEY NA,K-ATPASE AND MUSCLE CA-ATPASE FROM RABBIT AND SWINE
    BROGREN, CH
    ANDERSEN, JP
    HANSEN, O
    COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY A-PHYSIOLOGY, 1988, 90 (04): : 812 - 812
  • [36] Inhibition of Na,K-ATPase activity by local anesthetics in rat brain and rabbit brain and kidney
    Suzuki, K
    Kawada, I
    Iida, A
    Ono, S
    Deyama, Y
    Nishikata, M
    Matsumoto, A
    NA/K-ATPASE AND RELATED ATPASES, 2000, 1207 : 747 - 750
  • [37] HEPATIC NA,K-ATPASE DEVELOPMENT IN THE RAT
    DUFFY, LF
    KARL, PI
    DAUM, F
    FISHER, SE
    JOURNAL OF PEDIATRIC GASTROENTEROLOGY AND NUTRITION, 1988, 7 (06): : 894 - 901
  • [38] Hypertension driven by rapid decrease in PT Na,K-ATPase activity and increase in TALH Na,K-ATPase activity
    Zhang, YB
    Magyar, CE
    Holstein-Rathlou, NH
    McDonough, AA
    FASEB JOURNAL, 1998, 12 (04): : A421 - A421
  • [39] Effect of antioxidants on renal Na,K-atpase activity and expression
    Silva, E.
    Soares-da-Silva, P.
    JOURNAL OF HYPERTENSION, 2007, 25 : S394 - S394
  • [40] ETHANOL AND PLACENTAL NA,K-ATPASE ACTIVITY
    FISHER, SE
    ATKINSON, MB
    ALCOHOLISM-CLINICAL AND EXPERIMENTAL RESEARCH, 1984, 8 (01) : 90 - 90
12345