The clinical picture of drug allergies is very heterogeneous. A firm diagnosis requires first the exact description of the clinical history, including both the semiology and chronology of the case, The European Network of Drug Allergy (ENDA), under the aegis of the European Academy of Allergy and Clinical Immunology (EAACI), has recently published a standardized questionnaire, including both clinical data and results of the allergological tests. This questionnaire has been translated into questionnaire different languages. (C) 2000 Editions scientifiques et medicales Elsevier SAS.