Sialic acid imprinted polymer-coated quartz crystal microbalance

被引:0
|
作者
Kugimiya, A [1 ]
Yoneyama, H [1 ]
Takeuchi, T [1 ]
机构
[1] Hiroshima City Univ, Fac Informat Sci, Lab Synthet Biochem, Asaminami Ku, Hiroshima 7313194, Japan
关键词
sialic acid; polymer coated quartz crystal microbalance sensors; p-vinylbenzeneboronic acid; N; N-trimethylaminoethyl methacrylate;
D O I
暂无
中图分类号
O65 [分析化学];
学科分类号
070302 ; 081704 ;
摘要
Molecularly imprinted polymer-coated sensors for sialic acid were developed using a 9 MHz AT-cut quartz crystal microbalance (QCM). Recognition chips of the sensors used in this study were prepared by coating the two types of sialic acid-imprinted polymers with the use of p-vinylbenzeneboronic acid and/or N,N,N-trimethylaminoethyl methacrylate onto QCM. Each piezoelectric sensor showed a selective response to sialic acid and gave a linear relationship between frequency shift and amount of sialic acid from 20 to 250 nmol.
引用
收藏
页码:1322 / 1326
页数:5
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