Intraoperative Functional Ultrasound Imaging of Human Brain Activity

被引：77
|
作者：
Imbault, Marion [1 ]
Chauvet, Dorian [2 ,3 ]
Gennisson, Jean-Luc [1 ]
Capelle, Laurent [2 ]
Tanter, Mickael [1 ]
机构：
[1] PSL Res Univ, ESPCI ParisTech, CNRS, Inst Langevin Ondes & Images,UMR 7587,INSERM,U979, 17 Rue Moreau, F-75012 Paris, France
[2] Grp Hosp Pitie Salpetriere, Serv Neurochirurg, Batiment Babinski 47-83 Blvd Hop, F-75013 Paris, France
[3] Fdn Adolphe De Rothschild, Serv Neurochirurg, 29 Rue Manin, F-75019 Paris, France
来源：
SCIENTIFIC REPORTS | 2017年 / 7卷
基金：
欧洲研究理事会;
关键词：
COLUMN-ADDRESSED ARRAYS; MOVING BLOOD-VOLUME; DOPPLER; SURGERY; STIMULATION; TOMOGRAPHY; SIGNALS;
D O I：
10.1038/s41598-017-06474-8
中图分类号：
O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];
学科分类号：
07 ; 0710 ; 09 ;
摘要：
The functional mapping of brain activity is essential to perform optimal glioma surgery and to minimize the risk of postoperative deficits. We introduce a new, portable neuroimaging modality of the human brain based on functional ultrasound (fUS) for deep functional cortical mapping. Using plane-wave transmissions at an ultrafast frame rate (1 kHz), fUS is performed during surgery to measure transient changes in cerebral blood volume with a high spatiotemporal resolution (250 mu m, 1 ms). fUS identifies, maps and differentiates regions of brain activation during task-evoked cortical responses within the depth of a sulcus in both awake and anaesthetized patients.
引用
收藏
页数：7
相关论文
共 50 条
  • [31] Intraoperative imaging of the brain
    Lunsford, LD
    Kondziolka, D
    Bissonette, DJ
    STEREOTACTIC AND FUNCTIONAL NEUROSURGERY, 1996, 66 (1-3) : 58 - 64
  • [32] Real-time imaging of brain activity in freely moving rats using functional ultrasound
    Urban A.
    Dussaux C.
    Martel G.
    Brunner C.
    Mace E.
    Montaldo G.
    Nature Methods, 2015, 12 (9) : 873 - 878
  • [33] Real-time imaging of brain activity in freely moving rats using functional ultrasound
    Urban, Alan
    Dussaux, Clara
    Martel, Guillaume
    Brunner, Clement
    Mace, Emilie
    Montaldo, Gabriel
    NATURE METHODS, 2015, 12 (09) : 873 - +
  • [34] Spatiotemporal imaging of human brain activity by functional near-infrared spectroscopy
    Hoshi, Y
    Chen, SJ
    Tamura, M
    AMERICAN LABORATORY, 2001, 33 (20) : 35 - +
  • [35] Functional magnetic resonance imaging of human brain activity in a verbal fluency task
    Schlösser, R
    Hutchinson, M
    Joseffer, S
    Rusinek, H
    Saarimaki, A
    Stevenson, J
    Dewey, SL
    Brodie, JD
    JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY, 1998, 64 (04): : 492 - 498
  • [36] Harmonic imaging of the human brain - Visualization of brain perfusion with ultrasound
    Seidel, G
    Algermissen, C
    Christoph, A
    Claassen, L
    Vidal-Langwasser, M
    Katzer, T
    STROKE, 2000, 31 (01) : 151 - 154
  • [37] Accelerated parallel imaging for functional imaging of the human brain
    de Zwart, JA
    van Gelderen, P
    Golay, X
    Ikonomidou, VN
    Duyn, JH
    NMR IN BIOMEDICINE, 2006, 19 (03) : 342 - 351
  • [38] Application of functional imaging, neuronavigation, and intraoperative MR imaging in the surgical treatment of brain cavernomas
    Winter, Fabian
    Blair, Lisa
    Buchfelder, Michael
    Roessler, Karl
    NEUROLOGICAL RESEARCH, 2021, 43 (04) : 278 - 282
  • [39] Functional neuronavigation and intraoperative MR-imaging in brain tumour surgery
    Trantakis, C
    Seifert, V
    Winkler, D
    Dannenberg, C
    Strauss, G
    Bublat, M
    CARS 2001: COMPUTER ASSISTED RADIOLOGY AND SURGERY, 2001, 1230 : 276 - 279
  • [40] DYNAMIC INTRAOPERATIVE IMAGING AND INSTRUMENTATION OF BRAIN AND SPINAL-CORD USING ULTRASOUND
    DOHRMANN, GJ
    RUBIN, JM
    NEUROLOGIC CLINICS, 1985, 3 (02) : 425 - 437
12345