Intraoperative Functional Ultrasound Imaging of Human Brain Activity

被引:77
|
作者
Imbault, Marion [1 ]
Chauvet, Dorian [2 ,3 ]
Gennisson, Jean-Luc [1 ]
Capelle, Laurent [2 ]
Tanter, Mickael [1 ]
机构
[1] PSL Res Univ, ESPCI ParisTech, CNRS, Inst Langevin Ondes & Images,UMR 7587,INSERM,U979, 17 Rue Moreau, F-75012 Paris, France
[2] Grp Hosp Pitie Salpetriere, Serv Neurochirurg, Batiment Babinski 47-83 Blvd Hop, F-75013 Paris, France
[3] Fdn Adolphe De Rothschild, Serv Neurochirurg, 29 Rue Manin, F-75019 Paris, France
来源
SCIENTIFIC REPORTS | 2017年 / 7卷
基金
欧洲研究理事会;
关键词
COLUMN-ADDRESSED ARRAYS; MOVING BLOOD-VOLUME; DOPPLER; SURGERY; STIMULATION; TOMOGRAPHY; SIGNALS;
D O I
10.1038/s41598-017-06474-8
中图分类号
O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];
学科分类号
07 ; 0710 ; 09 ;
摘要
The functional mapping of brain activity is essential to perform optimal glioma surgery and to minimize the risk of postoperative deficits. We introduce a new, portable neuroimaging modality of the human brain based on functional ultrasound (fUS) for deep functional cortical mapping. Using plane-wave transmissions at an ultrafast frame rate (1 kHz), fUS is performed during surgery to measure transient changes in cerebral blood volume with a high spatiotemporal resolution (250 mu m, 1 ms). fUS identifies, maps and differentiates regions of brain activation during task-evoked cortical responses within the depth of a sulcus in both awake and anaesthetized patients.
引用
收藏
页数:7
相关论文
共 50 条
  • [1] Intraoperative Functional Ultrasound Imaging of Human Brain Activity
    Marion Imbault
    Dorian Chauvet
    Jean-Luc Gennisson
    Laurent Capelle
    Mickael Tanter
    Scientific Reports, 7
  • [2] Functional Ultrasound Imaging of the Human Brain Activity: An Intraoperative Pilot Study for Cortical Functional Mapping
    Imbault, M.
    Serroune, H.
    Gennisson, J. L.
    Tanter, M.
    Chauvet, D.
    Capelle, L.
    Lehericy, S.
    2016 IEEE INTERNATIONAL ULTRASONICS SYMPOSIUM (IUS), 2016,
  • [3] Functional ultrasound imaging of brain activity in human newborns
    Demene, Charlie
    Baranger, Jerome
    Bernal, Miguel
    Delanoe, Catherine
    Auvin, Stephane
    Biran, Valerie
    Alison, Marianne
    Mairesse, Jerome
    Harribaud, Elisabeth
    Pernot, Mathieu
    Tanter, Mickael
    Baud, Olivier
    SCIENCE TRANSLATIONAL MEDICINE, 2017, 9 (411)
  • [4] Functional Ultrasound Imaging of the Brain Activity in Human Neonates
    Demene, Charlie
    Bernal, Miguel
    Delanoe, Catherine
    Auvin, Stephane
    Biran, Valerie
    Alison, Marianne
    Mairesse, Jerome
    Harribaud, Elisabeth
    Pernot, Mathieu
    Tanter, Mickael
    Baud, Olivier
    2016 IEEE INTERNATIONAL ULTRASONICS SYMPOSIUM (IUS), 2016,
  • [5] Intraoperative infrared functional imaging of human brain
    Gorbach, AM
    Heiss, J
    Kufta, C
    Sato, S
    Fedio, P
    Kammerer, WA
    Solomon, J
    Oldfield, EH
    ANNALS OF NEUROLOGY, 2003, 54 (03) : 297 - 309
  • [6] Functional ultrasound imaging of human brain activity through an acoustically transparent cranial window
    Rabut, Claire
    Norman, Sumner L.
    Griggs, Whitney S.
    Russin, Jonathan J.
    Jann, Kay
    Christopoulos, Vasileios
    Liu, Charles
    Andersen, Richard A.
    Shapiro, Mikhail G.
    SCIENCE TRANSLATIONAL MEDICINE, 2024, 16 (749)
  • [7] Functional ultrasound imaging of the brain
    Mace, Emilie
    Montaldo, Gabriel
    Cohen, Ivan
    Baulac, Michel
    Fink, Mathias
    Tanter, Mickael
    NATURE METHODS, 2011, 8 (08) : 662 - U85
  • [8] Functional ultrasound imaging of the brain
    MacÉ E.
    Montaldo G.
    Cohen I.
    Baulac M.
    Fink M.
    Tanter M.
    Nature Methods, 2011, 8 (8) : 662 - 664
  • [9] Functional ultrasound imaging of brain activity : from small animal imaging to clinical applications
    Tanter, M.
    Osmanski, B.
    Demene, C.
    Pernot, M.
    Gennisson, J-L
    Fink, M.
    Biran, V.
    Baud, O.
    Sieu, L-A
    Cohen, I.
    CEREBROVASCULAR DISEASES, 2013, 35 : 9 - 10
  • [10] Intraoperative optical imaging of epileptiform and functional activity
    Haglund, MM
    NEUROSURGERY CLINICS OF NORTH AMERICA, 1997, 8 (03) : 413 - +