Dual inhibition of CDK4 and FYN leads to selective cell death in KRAS-mutant colorectal cancer

被引:8
|
作者
Wang, Yan [1 ]
Lin, Rongjie [1 ,2 ]
Ling, Huan [1 ]
Ke, Yuan [1 ]
Zeng, Yangyang [1 ]
Xiong, Yudi [1 ]
Zhou, Qian [1 ]
Zhou, Fuxiang [1 ,3 ]
Zhou, Yunfeng [1 ,3 ]
机构
[1] Hubei Key Lab Tumor Biol Behav, Wuhan, Hubei, Peoples R China
[2] Fujian Med Univ, Fujian Canc Hosp, Dept Radiat Oncol, Canc Hosp, Fuzhou, Fujian, Peoples R China
[3] Wuhan Univ, Zhongnan Hosp, Dept Radiat & Med Oncol, Wuhan, Hubei, Peoples R China
基金
中国国家自然科学基金;
关键词
D O I
10.1038/s41392-019-0088-z
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
引用
收藏
页数:3
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