Quantitative trait loci for BMD and bone strength in an intercross between domestic and wildtype chickens

被引：27

作者：

Rubin, Carl-Johan

Brandstrom, Helena

Wright, Dominic

Kerje, Susanne

Gunnarsson, Ulrika

Schutz, Karin

Fredriksson, Robert

Jensen, Per

Andersson, Leif

Ohlsson, Claes

Mallmin, Hans

Larsson, Sune

Kindmark, Andreas ^{[1
]}

机构：

[1] Univ Uppsala Hosp, Dept Med Sci, SE-75185 Uppsala, Sweden

[2] Univ Uppsala Hosp, Dept Med Biochem & Microbiol, SE-75185 Uppsala, Sweden

[3] AgResearch, Hamilton, New Zealand

[4] Univ Uppsala Hosp, Dept Neurosci, SE-75185 Uppsala, Sweden

[5] Linkoping Univ, IFM, Linkoping, Sweden

[6] Swedish Univ Agr Sci, Dept Anim Breeding & Genet, S-75007 Uppsala, Sweden

[7] Univ Gothenburg, Sahlgrenska Hosp, Div Endocrinol, Dept Internal Med, Gothenburg, Sweden

[8] Univ Uppsala Hosp, Dept Surg Sci, Sect Orthoped, SE-75185 Uppsala, Sweden

来源：

JOURNAL OF BONE AND MINERAL RESEARCH | 2007年 / 22卷 / 03期

关键词：

chicken; quantitative trait loci; BMD; biomechanics;

D O I：

10.1359/JBMR.061203

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

With chicken used as a model species, we used QTL analysis to examine the genetic contribution to bone traits. We report the identification of four QTLs for femoral traits: one for bone strength, one for endosteal circumference, and two affecting mineral density of noncortical bone.

引用

页码：375 / 384

页数：10

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