Main Alkaloids of Securinega suffruticosa. Nitrogen Atom Inversion in Securinine

被引：0
|
作者：
Kurbanov, U. Kh. [1 ]
Tashkhodjaev, B. [1 ]
Levkovich, M. G. [1 ]
Bruskov, V. P. [1 ]
Mukarramov, N. I. [1 ]
Abdullaev, N. D. [1 ]
机构：
[1] Acad Sci Uzbek, Yunusov Inst Chem Plant Subst, Tashkent, Uzbekistan
来源：
JOURNAL OF STRUCTURAL CHEMISTRY | 2019年 / 60卷 / 09期
关键词：
securinine; allosecurinine; securitinine; nitrogen inversion; single crystal XRD; NMR spectroscopy; computational methods; MOLECULAR-STRUCTURE; CRYSTAL-STRUCTURE; HYDROBROMIDE;
D O I：
10.1134/S0022476619090142
中图分类号：
O61 [无机化学];
学科分类号：
070301 ; 081704 ;
摘要：
The main alkaloids such as securinine (1), allosecurinine (2), and securitinine (3) are isolated from the Securinega suffruticosa plant and identified by spectral techniques. The spatial structure of 3 is determined by single crystal XRD. The inversion of the pyramidal-tetrahedral nitrogen atom of compound 1 in the crystal and the solution is analyzed based on single crystal XRD and NMR spectroscopy data. By the computational methods and NMR spectroscopy it is shown that the configuration of the nitrogen atom in securinine is related to the alkaloid salt formation rather than the crystal field effect (packing factor).
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收藏
页码：1489 / 1495
页数：7
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