Challenges and research progress of the use of mesenchymal stem cells in the treatment of ischemic stroke

被引：12
|
作者：
Jiang, Jipeng [1 ]
Wang, Yuting [2 ]
Liu, Baohu [3 ]
Chen, Xuyi [1 ]
Zhang, Sai [1 ]
机构：
[1] Logist Univ Peoples Armed Police Forces, Inst Brain Trauma & Neurol Dis, Affiliated Hosp, Chenglin Rd 220, Tianjin 300162, Peoples R China
[2] Tianjin Med Univ, Qixiangtai Rd 22, Tianjin 300070, Peoples R China
[3] Tianjin Univ Tradit Chinese Med, Yuquan Rd 88, Tianjin 300193, Peoples R China
来源：
BRAIN & DEVELOPMENT | 2018年 / 40卷 / 07期
基金：
中国国家自然科学基金;
关键词：
Ischemic stroke; Stem cells; Mesenchymal stem cells; Transplantation; PARASYMPATHETIC SPHENOPALATINE GANGLION; MARROW STROMAL CELLS; IN-VIVO DISTRIBUTION; BONE-MARROW; CORD BLOOD; INTRAARTERIAL DELIVERY; THERAPEUTIC BENEFIT; GLOBAL BURDEN; RAT MODEL; SAFETY;
D O I：
10.1016/j.braindev.2018.03.015
中图分类号：
R74 [神经病学与精神病学];
学科分类号：
摘要：
Cerebral Ischemic Stroke (CIS) has become a hot issue in medical research because of the diversity of risk factors and the uncertainty of prognosis. in the field of regenerative medicine, mesenchymal stern cells (MSCs) have an increasingly prominent position due to their advantages of multiple differentiation, low immunogenicity and wide application. In the basic and clinical research of CIS, there are still some problems to be solved in the treatment of CIS. This paper will discuss the progresses and some obstacles of current MSCs for the treatment of CIS. (C) 2018 The Japanese Society of Child Neurology. Published by Elsevier B.V. All rights reserved.
引用
收藏
页码：612 / 626
页数：15
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