Effective activation of chiral BINOL/Ti(OiPr)4 catalyst with phenolic additives for the enantioselective alkynylation of aldehydes

被引：52

作者：

Lu, G

Li, XS

Chen, G

Chan, WL ^{[1
]}

Chan, ASC

机构：

[1] Hong Kong Polytech Univ, Open Lab Chirotechnol, Inst Mol Technol Drug Discovery & Synth, Hong Kong, Hong Kong, Peoples R China

[2] Hong Kong Polytech Univ, Dept Appl Biol & Chem Technol, Hong Kong, Hong Kong, Peoples R China

来源：

TETRAHEDRON-ASYMMETRY | 2003年 / 14卷 / 04期

关键词：

D O I：

10.1016/S0957-4166(03)00021-1

中图分类号：

O61 [无机化学];

学科分类号：

070301 ; 081704 ;

摘要：

The activation of chiral titanium(IV) complexes With achiral activators. e.g. phenol. is found to provide higher levels of enantioselectivity than those attained with an enantiopure catalyst in the alkynylations of both aromatic and aliphatic aldehydes. (C) 2003 Elsevier Science Ltd. All rights reserved.

引用

页码：449 / 452

页数：4