Blue dye, green heart

被引：6
|
作者：
Tan, Carmela D. [1 ]
Rodriguez, E. Rene [1 ]
机构：
[1] Cleveland Clin, Dept Anat Pathol, Cleveland, OH 44195 USA
来源：
CARDIOVASCULAR PATHOLOGY | 2010年 / 19卷 / 02期
关键词：
Methylene blue; Cardiac myocardium; METHYLENE-BLUE; SHOCK;
D O I：
10.1016/j.carpath.2008.06.012
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
Methylene blue has been used for the rapid reversal of circulatory shock refractory to fluid administration, inotropic agents, and vasoconstrictors. Its clinical side effects have been well described. We report an interesting autopsy observation in patients who received methylene blue as adjunct therapy for septic shock. The exposed surface of cardiac myocardium on both fresh and fixed states rapidly turned green. In the presence of molecular oxygen, the colorless metabolite leukomethylene blue is readily oxidized to methylene blue, thus explaining the visible color change of the myocardium. (C) 2010 Elsevier Inc. All rights reserved.
引用
收藏
页码：125 / 126
页数：2
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