Ethyl 1,6-dimethyl-2-oxo-4-(quinolin-4-yl)-1,2,3,4-tetrahydropyrimidine-5-carboxylate

被引:0
|
作者
Zubatyuk, Roman I. [1 ]
Shishkin, Oleg V. [1 ]
Ihmels, Heiko [2 ]
Lebedyeva, Iryna A. [3 ]
Povstyanoy, Mykhaylo V. [3 ]
机构
[1] STC Inst Single Crystals NAS Ukraine, Kharkov, Ukraine
[2] Univ Siegen, D-57068 Siegen, Germany
[3] Kherson Natl Tech Univ, Dept Organ & Biochem Synth, UA-73008 Kherson, Ukraine
关键词
DNA; QUINOLINE;
D O I
10.1107/S1600536810023482
中图分类号
O7 [晶体学];
学科分类号
0702 ; 070205 ; 0703 ; 080501 ;
摘要
In the title compound, C(18)H(19)N(3)O(3), the tetrahydropyrimidone ring adopts a distorted boat conformation. In the crystal structure, intermolecular N-H center dot center dot center dot O hydrogen bonds link the molecules into centrosymmetric dimers, which are further linked via intermolecular C-H center dot center dot center dot pi interactions. In addition, an intramolecular C-H center dot center dot center dot O hydrogen bond occurs.
引用
收藏
页码:O1762 / U232
页数:12
相关论文
共 50 条
  • [41] Ethyl 3-acetyl-4-(3-methoxyphenyl)-6-methyl-2-sulfanylidene-1,2,3,4-tetrahydropyrimidine-5-carboxylate
    Fathima, Nikhath
    Nagarajaiah, H.
    Begum, Noor Shahina
    ACTA CRYSTALLOGRAPHICA SECTION E-CRYSTALLOGRAPHIC COMMUNICATIONS, 2012, 68 : O1555 - +
  • [42] Ethyl 6-methyl-4-[2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)thiophen-3-yl]-2-thioxo-1,2,3,4-tetrahydropyrimidine-5-carboxylate
    Decken, Andreas
    Zamora, Matthew T.
    Duguay, Dominique R.
    Vogels, Christopher M.
    Westcott, Stephen A.
    ACTA CRYSTALLOGRAPHICA SECTION E-STRUCTURE REPORTS ONLINE, 2008, 64 : O929 - U2719
  • [43] Crystal structure of methyl 4-(4-hydroxyphenyl)-6-methyl-2-oxo-1,2,3,4-tetrahydropyrimidine-5-carboxylate monohydrate
    Bairagi, Keshab M.
    Venugopala, Katharigatta N.
    Mondal, Pradip Kumar
    Odhav, Bharti
    Nayak, Susanta K.
    ACTA CRYSTALLOGRAPHICA SECTION E-CRYSTALLOGRAPHIC COMMUNICATIONS, 2016, 72 : 1335 - +
  • [44] Methyl 4-(4-hydroxyphenyl)-6-methyl-2-sulfanylidene-1,2,3,4-tetrahydropyrimidine-5-carboxylate
    Fathima, Nikhath
    Nagarajaiah, H.
    Begum, Noor Shahina
    ACTA CRYSTALLOGRAPHICA SECTION E-CRYSTALLOGRAPHIC COMMUNICATIONS, 2014, 70 : O306 - +
  • [45] Thermodynamic properties of methyl 4-(4-methoxyphenyl)-6-methl-2-oxo-1,2,3,4-tetrahydropyrimidine-5-carboxylate in organic solutions
    Ridka, O.
    Matiychuk, V
    Sobechko, I
    Tyshchenko, N.
    Novyk, M.
    Sergeev, V
    Goshko, L.
    FRENCH-UKRAINIAN JOURNAL OF CHEMISTRY, 2019, 7 (02): : 1 - 8
  • [46] Crystal structure of ethyl 4-(2-fluoro-phenyl)-6-methyl-2-sulfanylidene-1,2,3,4-tetrahydropyrimidine-5-carboxylate
    Krishnamurthy, M. S.
    Begum, Noor Shahina
    ACTA CRYSTALLOGRAPHICA SECTION E-CRYSTALLOGRAPHIC COMMUNICATIONS, 2015, 71 : O699 - U139
  • [47] Synthesis and Hypotensive Activity of Novel Styryl Derivatives Based on Ethyl-4-(4-Methoxyphenyl)-2-Thioxo-1,2,3,4-Tetrahydropyrimidine-5-Carboxylate
    S. D. Fazylov
    O. A. Nurkenov
    T. S. Zhivotova
    A. E. Arinova
    I. S. Tolepbek
    A. N. Zhakupova
    R. E. Bakirova
    L. E. Muravleva
    Pharmaceutical Chemistry Journal, 2016, 50 : 440 - 442
  • [48] Synthesis and Hypotensive Activity of Novel Styryl Derivatives Based on Ethyl-4-(4-Methoxyphenyl)-2-Thioxo-1,2,3,4-Tetrahydropyrimidine-5-Carboxylate
    Fazylov, S. D.
    Nurkenov, O. A.
    Zhivotova, T. S.
    Arinova, A. E.
    Tolepbek, I. S.
    Zhakupova, A. N.
    Bakirova, R. E.
    Muravleva, L. E.
    PHARMACEUTICAL CHEMISTRY JOURNAL, 2016, 50 (07) : 440 - 442
  • [49] Synthesis and antioxidant evaluation of 4-(furan-2-yl)-6-methyl-2-thioxo-1,2,3,4-tetrahydropyrimidine-5-carboxylate esters
    Mansouri, M.
    Movahedian, A.
    Rostami, M.
    Fassihi, A.
    RESEARCH IN PHARMACEUTICAL SCIENCES, 2012, 7 (04) : 257 - 264
  • [50] Biginelli-like three component reaction: Synthesis of some new ethyl 6-ethoxycarbonylmethyl-4-aryl-2-oxo-1,2,3,4-tetrahydropyrimidine-5-carboxylate derivatives
    Azizian, Javad
    Mohammadi, Ali A.
    Kohshari, M.
    Karimi, Ali R.
    Mohammadizadeh, Mohammad R.
    JOURNAL OF HETEROCYCLIC CHEMISTRY, 2007, 44 (02) : 455 - 458