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Pyrrolizidine alkaloids
被引：137
|作者：
Robertson, Jeremy
[1
]
Stevens, Kiri
[1
]
机构：
[1] Univ Oxford, Chem Res Lab, Dept Chem, Oxford OX1 3TA, England
关键词：
1ST TOTAL-SYNTHESIS;
LANOSTEROL SYNTHASE INHIBITORS;
ASYMMETRIC TOTAL-SYNTHESIS;
NONCHIRAL-POOL SYNTHESIS;
FORMAL 3+2 ANNULATION;
POLYHYDROXYLATED PYRROLIZIDINES;
STEREOSELECTIVE-SYNTHESIS;
1,3-DIPOLAR CYCLOADDITION;
CONCISE SYNTHESIS;
EFFICIENT SYNTHESIS;
D O I：
10.1039/c4np00055b
中图分类号：
Q5 [生物化学];
Q7 [分子生物学];
学科分类号：
071010 ;
081704 ;
摘要：
This review covers pyrrolizidine alkaloids isolated from natural sources. Topics include: aspects of structure, isolation, and biological/pharmacological studies; total syntheses of necic acids, necine bases and closely-related non-natural analogues.
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页码：1721 / 1788
页数：68
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