?Rapid speed of response to ECT in bipolar depression: A chart review

被引：2

作者：

Scheepstra, K. W. F. ^{[1
,2
]}

van Doorn, J. B. ^{[3
]}

Scheepens, D. S. ^{[1
]}

de Haan, A. ^{[1
]}

Schukking, N. ^{[1
]}

Zantvoord, J. B. ^{[1
]}

Lok, A. ^{[1
]}

机构：

[1] Univ Amsterdam, Dept Psychiat, Locat AMC, Amsterdam UMC, Meibergdreef 9, NL-1105 AZ Amsterdam, Netherlands

[2] Netherlands Inst Neurosci, Neuroimmunol Res Grp, Meibergdreef 47, NL-1105 BA Amsterdam, Netherlands

[3] Univ Amsterdam, Dept Psychol Methods, Valckeniersstr 59, NL-1018 XA Amsterdam, Netherlands

来源：

JOURNAL OF PSYCHIATRIC RESEARCH | 2022年 / 147卷

关键词：

Electroconvulsive therapy; Major depressive disorder; Bipolar disorder; Depression; ELECTROCONVULSIVE-THERAPY; MAJOR DEPRESSION; REMISSION; EFFICACY; DISORDER;

D O I：

10.1016/j.jpsychires.2022.01.008

中图分类号：

R749 [精神病学];

学科分类号：

100205 ;

摘要：

Objective: To validate a faster speed of response to electroconvulsive therapy (ECT) for bipolar depression (BPD) compared to major depressive disorder (MDD)& nbsp;Method: Retrospective chart review on an ECT cohort in an academic hospital setting. Speed of response was defined by the number of ECT treatments needed for response or remission.& nbsp;Results: Sixty-four depressed patients were included, of whom 53 (MDD: 40, BPD: 13) could be analyzed. The bipolar group responded faster with a mean difference of 3.3 fewer ECT treatments to meet response criteria (MDD 10.4 vs. BPD 7.1, p = 0.054). When using mixed effects regression models for the response/remitter group (n = 35), a faster response for the bipolar group (AIC 252.83 vs 258.55, chi(2) =11.72, p = 0.008) was shown. Other factors, such as psychotic features or comorbidity, did not influence the speed of response.& nbsp;Conclusion: This chart review of an ECT cohort in an naturalistic academic hospital setting shows an evident and clinically relevant faster speed of response in bipolar depression.

引用

页码：34 / 38

页数：5

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