2,4,6-trichloropyrimidine. Reaction with 4-substituted phenolate ions

被引:17
|
作者
Delia, TJ [1 ]
Nagarajan, A [1 ]
机构
[1] Cent Michigan Univ, Dept Chem, Malcolm H Filson Labs, Mt Pleasant, MI 48859 USA
关键词
D O I
10.1002/jhet.5570350201
中图分类号
O62 [有机化学];
学科分类号
070303 ; 081704 ;
摘要
A systematic investigation of the reactivity of 2,4,6-trichloropyrimidine with phenoxide nucleophiles has been conducted. Conditions have been described which lead to mono-, di-, and trisubstituted-pyrimidines. Unexpected product distributions for mono-and disubstituted products were observed and explanations for these results are offered.
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页码:269 / 273
页数:5
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