Antiviral and anti-inflammatory therapies in COVID-19

被引:11
|
作者
Szekanecz Zoltan [1 ]
Bogos Krisztina [2 ]
Constantin Tamas [3 ]
Fullesdi Bela [4 ]
Muller Veronika [5 ]
Rakoczi Eva [1 ]
Varkonyi Istvan [6 ]
Valyi-Nagy Istvan [7 ]
机构
[1] Debreceni Egyet, Altalanos Orvostud Kar, Belgyogyaszati Klin, Reumatol, Debrecen, Hungary
[2] Orszagos Koranyi Pulmonol Int, Budapest, Hungary
[3] Semmelweis Egyet, Altalanos Orvostud Kar, Gyermekgyogyaszati Klin 2, Budapest, Hungary
[4] Debreceni Egyet, Altalanos Orvostud Kar, Aneszteziol & Intenz Terapias Klin, Debrecen, Hungary
[5] Semmelweis Egyet, Altalanos Orvostud Kar, Pulmonol Klin, Budapest, Hungary
[6] Debreceni Egyet, Altalanos Orvostud Kar, Infektol Klin, Debrecen, Hungary
[7] Del Pesti Ctr Korhaz, Orszagos Hematol & Infektol Int, Budapest, Hungary
关键词
novel coronavirus infection (COVID-19); coronavirus; cytokine storm; antiviral treatment; cytokine in-hibition treatment; corticosteroid; interleukin-6; inhibition; Janus kinase inhibition; intravenous immunoglobulin; TOCILIZUMAB; MULTICENTER;
D O I
10.1556/650.2021.32230
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
The novel coronavirus infection (COVID-19) places a heavy burden on the health care system and our society. There are three major stages in the disease that fundamentally determine treatment approaches. Phases I?IIA require primarily antiviral treatment. In phases IIB?III, anti-inflammatory treatment is needed accompanied by intensive and supportive care. This recommendation applies only to pharmacotherapy and summarizes the therapeutic options based on the available evidence. It also includes a proposed treatment algorithm.
引用
收藏
页码:643 / 651
页数:9
相关论文
共 50 条
  • [21] The Benefits of Heparin Use in COVID-19: Pleiotropic Antiviral Activity beyond Anticoagulant and Anti-Inflammatory Properties
    Lippi, Giuseppe
    Henry, Brandon M.
    Favaloro, Emmanuel J.
    SEMINARS IN THROMBOSIS AND HEMOSTASIS, 2023, 49 (01): : 73 - 75
  • [22] Outcome of COVID-19 in interstitial lung disease patients treated with anti-inflammatory drugs and antiviral drugs
    Yamaya, Takafumi
    Hagiwara, Eri
    Baba, Tomohisa
    Iwasawa, Tae
    Ogura, Takashi
    JOURNAL OF INFECTION AND CHEMOTHERAPY, 2022, 28 (07) : 1029 - 1032
  • [23] Anti-Inflammatory and Antiviral Osmotic Polymeric Film to Treat Covid-19 Early-Stage Infection
    Shrivastava, Ravi
    Shrivastava, Remi
    Johansen, Bianca
    Allain, Thibault
    JOURNAL OF INFLAMMATION RESEARCH, 2021, 14 : 1195 - 1206
  • [24] The outcome of COVID-19 in interstitial lung disease patients treated with anti-inflammatory drugs and antiviral drugs
    Yamaya, Takafumi
    Hagiwara, Eri
    Baba, Tomohisa
    Iwasawa, Tae
    Ogura, Takashi
    EUROPEAN RESPIRATORY JOURNAL, 2021, 58
  • [25] COVID-19, POST-COVID. ANTI-INFLAMMATORY THERAPEUTIC INTERVENTIONS
    Athanassiou, P.
    AGING CLINICAL AND EXPERIMENTAL RESEARCH, 2022, 34 (SUPPL 1) : S91 - S91
  • [26] Non-steroidal anti-inflammatory drugs and covid-19
    Little, Paul
    BMJ-BRITISH MEDICAL JOURNAL, 2020, 368
  • [27] Anti-Inflammatory Effects of Immunostimulation in Patients with COVID-19 Pneumonia
    Santus, Pierachille
    Radovanovic, Dejan
    Garziano, Micaela
    Pini, Stefano
    Croce, Giuseppe
    Fuccia, Giuseppe
    Spitaleri, Debora
    Biasin, Mara
    Clerici, Mario
    Trabattoni, Daria
    JOURNAL OF CLINICAL MEDICINE, 2021, 10 (24)
  • [28] Finding the right time for anti-inflammatory therapy in COVID-19
    de Simone, Giovanni
    Mancusi, Costantino
    INTERNATIONAL JOURNAL OF INFECTIOUS DISEASES, 2020, 101 : 247 - 248
  • [29] Use of Psychotropics in COVID-19: Another Anti-inflammatory Pathway
    Morillo, Jessenia
    Morillo, Valery
    Marquina, Maria Angelica
    Rojas, Milagros
    Nava, Manuel
    CURRENT PSYCHIATRY RESEARCH AND REVIEWS, 2023, 19 (02) : 137 - 146
  • [30] Repositioning Chromones for Early Anti-inflammatory Treatment of COVID-19
    Sestili, Piero
    Stocchi, Vilberto
    FRONTIERS IN PHARMACOLOGY, 2020, 11